Publications of Michael Wierer

Greulich, F.; Wierer, M.; Mechtidou, A.; Gonzalez-Garcia, O.; Uhlenhaut, N. H.: The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers. Cell Reports 34 (6), 108742 (2021)

Bartoschek, M. D.; Ugur, E.; Nguyen, T.-A.; Rodschinka, G.; Wierer, M.; Lang, K.; Bultmann, S.: Identification of permissive amber suppression sites for efficient non-canonical amino acid incorporation in mammalian cells. Nucleic Acids Research (London) 49 (11), e62 (2021)

Dang, T. A.; Kessler, T.; Wobst, J.; Wierer, M.; Braenne, I.; Strom, T. M.; Tennstedt, S.; Sager, H. B.; Meitinger, T.; Erdmann, J. et al.; Schunkert, H.: Identification of a Functional PDE5A Variant at the Chromosome 4q27 Coronary Artery Disease Locus in an Extended Myocardial Infarction Family. Circulation 144 (8), pp. 662 - 665 (2021)

Hoefig, K. P.; Reim, A.; Gallus, C.; Wong, E. H.; Behrens, G.; Conrad, C.; Xu, M.; Kifinger, L.; Ito-Kureha, T.; Defourny, K. A. Y. et al.; Geerlof, A.; Mautner, J.; Hauck, S. M.; Baumjohann, D.; Feederle, R.; Mann, M.; Wierer, M.; Glasmacher, E.; Heissmeyer, V.: Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation. Nature Communications 12 (1), 5208 (2021)

Qin, W.; Ugur, E.; Mulholland, C. B.; Bultmann, S.; Solovei, I.; Modic, M.; Smets, M.; Wierer, M.; Forne, I.; Imhof, A. et al.; Cardoso, M. C.; Leonhardt, H.: Phosphorylation of the HP1 beta hinge region sequesters KAP1 in heterochromatin and promotes the exit from naive pluripotency. Nucleic Acids Research 49 (13), pp. 7406 - 7423 (2021)

von Scheidt, M.; Zhao, Y.; de Aguiar Vallim, T. Q.; Che, N.; Wierer, M.; Seldin, M. M.; Franzen, O.; Kurt, Z.; Pang, S.; Bongiovanni, D. et al.; Yamamoto, M.; Edwards, P. A.; Ruusalepp, A.; Kovacic, J. C.; Mann, M.; Bjorkegren, J. L. M.; Lusis, A. J.; Yang, X.; Schunkert, H.: Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism. Circulation 143 (18), pp. 1809 - 1823 (2021)

Wierer, M.; Werner, J.; Wobst, J.; Kastrati, A.; Cepele, G.; Aherrahrou, R.; Sager, H. B.; Erdmann, J.; Dichgans, M.; Flockerzi, V. et al.; Civelek, M.; Dietrich, A.; Mann, M.; Schunkert, H.; Kessler, T.: A proteomic atlas of the neointima identifies novel druggable targets for preventive therapy. European Heart Journal 42 (18), pp. 1773 - 1785 (2021)

Reim, A.; Ackermann, R.; Font-Mateu, J.; Kammel, R.; Beato, M.; Nolte, S.; Mann, M.; Russmann, C.; Wierer, M.: Atomic-resolution mapping of transcription factor-DNA interactions by femtosecond laser crosslinking and mass spectrometry. Nature Communications 11 (1), 3019 (2020)

Escoter-Torres, L.; Greulich, F.; Quagliarini, F.; Wierer, M.; Uhlenhaut, N. H.: Anti-inflammatory functions of the glucocorticoid receptor require DNA binding. Nucleic Acids Research (London) 48 (15), pp. 8393 - 8407 (2020)

Mulholland, C. B.; Nishiyama, A.; Ryan, J.; Nakamura, R.; Yigit, M.; Glueck, I. M.; Trummer, C.; Qin, W.; Bartoschek, M. D.; Traube, F. R. et al.; Parsa, E.; Ugur, E.; Modic, M.; Acharya, A.; Stolz, P.; Ziegenhain, C.; Wierer, M.; Enard, W.; Carell, T.; Lamb, D. C.; Takeda, H.; Nakanashi, M.; Bultmann, S.; Leonhardt, H.: Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals. Nature Communications 11 (1), 5972 (2020)

Scacchetti, A.; Schauer, T.; Reim, A.; Apostolou, Z.; Sparr, A. C.; Krause, S.; Heun, P.; Wierer, M.; Becker, P. B.: Drosophila SWR1 and NuA4 complexes are defined by DOMINO isoforms. ELIFE 9, e56325 (2020)

Hemmer, M. C.; Wierer, M.; Schachtrup, K.; Downes, M.; Huebner, N.; Evans, R. M.; Uhlenhaut, N. H.: E47 modulates hepatic glucocorticoid action. Nature Communications 10, 306 (2019)

Quagliarini, F.; Mir, A. A.; Balazs, K.; Wierer, M.; Dyar, K. A.; Jouffe, C.; Makris, K.; Hawe, J.; Heinig, M.; Filipp, F. V. et al.; Barish, G. D.; Uhlenhaut, N. H.: Cistromic Reprogramming of the Diurnal Glucocorticoid Hormone Response by High-Fat Diet. MOLECULAR CELL 76 (4), pp. 531 - 545.e5 (2019)

Quarta, C.; Fisette, A.; Xu, Y.; Collden, G.; Legutko, B.; Tseng, Y.-T.; Reim, A.; Wierer, M.; De Rosa, M. C.; Klaus, V. et al.; Rausch, R.; Thaker, V. V.; Graf, E.; Strom, T. M.; Poher, A.-L.; Gruber, T.; Le Thuc, O.; Cebrian-Serrano, A.; Kabra, D.; Bellocchio, L.; Woods, S. C.; Pflugfelder, G. O.; Nogueiras, R.; Zeltser, L.; Kadow, I. C. G.; Moon, A.; Garcia-Caceres, C.; Mann, M.; Treier, M.; Doege, C. A.; Tschoep, M. H.: Functional identity of hypothalamic melanocortin neurons depends on Tbx3. NATURE METABOLISM 1 (2), pp. 222 - 235 (2019)

Wierer, M.; Prestel, M.; Schiller, H. B.; Yan, G.; Schaab, C.; Azghandi, S.; Werner, J.; Kessler, T.; Malik, R.; Murgia, M. et al.; Aherrahrou, Z.; Schunkert, H.; Dichgans, M.; Mann, M.: Compartment-resolved Proteomic Analysis of Mouse Aorta during Atherosclerotic Plaque Formation Reveals Osteoclast-specific Protein Expression. Molecular and Cellular Proteomics 17 (2), pp. 321 - 334 (2018)

Coscia, F.; Lengyel, E.; Duraiswamy, J.; Ashcroft, B.; Bassani-Sternberg, M.; Wierer, M.; Johnson, A.; Wroblewski, K.; Montag, A.; Yamada, S. D. et al.; Lopez-Mendez, B.; Nilsson, J.; Mund, A.; Mann, M.; Curtis, M.: Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer. Cell 175 (1), pp. 159 - 170.e16 (2018)

Doll, S.; Kriegmair, M. C.; Santos, A.; Wierer, M.; Coscia, F.; Neil, H. M.; Porubsky, S.; Geyer, P. E.; Mund, A.; Nuhn, P. et al.; Mann, M.: Rapid proteomic analysis for solid tumors reveals LSD1 as a drug target in an end-stage cancer patient. Molecular Oncology 12 (8), pp. 1296 - 1307 (2018)

Wierer, M.; Mann, M.: Proteomics to study DNA-bound and chromatin-associated gene regulatory complexes. Human Molecular Genetics 25 (R2), pp. R106 - R114 (2016)

Wobst, J.; von Ameln, S.; Wolf, B.; Wierer, M.; Dang, T. A.; Sager, H. B.; Tennstedt, S.; Hengstenberg, C.; Koesling, D.; Friebe, A. et al.; Braun, S. L.; Erdmann, J.; Schunkert, H.; Kessler, T.: Stimulators of the soluble guanylyl cyclase: promising functional insights from rare coding atherosclerosis-related GUCY1A3 variants. Basic Research in Cardiology 111 (4), 51 (2016)

Beringer, M.; Pisano, P.; Di Carlo, V.; Blanco, E.; Chammas, P.; Vizan, P.; Gutierrez, A.; Aranda, S.; Payer, B.; Wierer, M. et al.; Di Croce, L.: EPOP Functionally Links Elongin and Polycomb in Pluripotent Stem Cells. Molecular Cell 64 (4), pp. 645 - 658 (2016)