Publications of M. Groll

Groll, M.; Huber, R.: Substrate access and processing by the 20S proteasome core particle. International Journal of Biochemistry & Cell Biology 35 (5), pp. 606 - 616 (2003)

Groll, M.; Brandstetter, H.; Bartunik, H.; Bourenkow, G.; Huber, R.: Investigations on the maturation and regulation of archaebacterial proteasomes. Journal of Molecular Biology 327 (1), pp. 75 - 83 (2003)

Kaiser, M.; Milbradt, A. G.; Renner, C.; Assfalg-Machleidt, I.; Groll, M.; Huber, R.; Moroder, L.: Cyclic biphenyl ether tripeptides as proteasome inhibitors. Biopolymers 71 (3), p. 396 - 396 (2003)

Kim, J. S.; Groll, M.; Musiol, H.-J.; Behrendt, R.; Kaiser, M.; Moroder, L.; Huber, R.; Brandstetter, H.: Navigation inside a protease: Substrate selection and product exit in the tricorn protease from Thermoplasma acidophilum. Journal of Molecular Biology 324 (5), pp. 1041 - 1050 (2002)

Goettig, P.; Groll, M.; Kim, J. S.; Huber, R.; Brandstetter, H.: Structures of the tricorn-interacting aminopeptidase F1 with different ligands explain its catalytic mechanism. EMBO Journal 21 (20), pp. 5343 - 5352 (2002)

Brandstetter, H.; Kim, J. S.; Groll, M.; Göttig, P.; Huber, R.: Structural basis for the processive protein degradation by tricorn protease. Biological Chemistry 383 (7-8), pp. 1157 - 1165 (2002)

Groll, M.; Nazif, T.; Huber, R.; Bogyo, M.: Probing structural determinants distal to the site of hydrolysis that control substrate specificity of the 20S proteasome. Chemistry & Biology 9 (5), pp. 655 - 662 (2002)

Kaiser, M.; Groll, M.; Renner, C.; Huber, R.; Moroder, L.: The core structure of TMC-95A is a promising lead for reversible proteasome inhibition. Angewandte Chemie-International Edition 41 (5), pp. 780 - 783 (2002)

Bochtler, M.; Groll, M.; Brandstetter, H.; Clausen, T.; Huber, R.: Molecular machines for protein degradation. Protein Degradation. In: Protein Degradation 1, pp. 248 - 287 (Eds. Mayer, R. J.; A., C.; Rechsteiner, M.). Wiley-VCH, Weinheim (2005)

Kaiser, M.; Groll, M.; Götz, M.; Siciliano, C.; Assfalg-Machleidt, I.; Weyher, E.; Kohno, J.; Milbradt, A. G.; Renner, C.; Huber, R. et al.; Moroder, L.: Structural determinants for 20S proteasome inhibition by TMC-95A. In: Peptides 2004, pp. 657 - 658 (Eds. Flegel, M.; Fridkin, M.; Gilon, C.; Slaninovva, J.). Kenes International, Geneva/Switzerland (2005)

Kaiser, M.; Groll, M.; Siciliano, C.; Götz, M.; Assfalg-Machleidt, I.; Kohno, J.; Milbradt, A. G.; Renner, C.; Huber, R.; Moroder, L.: Inhibition of yeast 20S proteasome by biaryl- and biaryl ether cross-bridged tripeptide derivatives as TMC-95A analogs. In: Peptides – Biology and Chemistry, pp. 201 - 225 (Eds. Liu, K.-L.; J. P., T.). Science Press, USA (2005)

Groll, M.; Huber, R.: Structures of the yeast proteasome core particle in complex with inhibitors. In: Cancer Drug Discovery and Development: Proteasome Inhibitors in Cancer Therapy, pp. 39 - 46 (Ed. Adams, J.). Humana Press Inc.,, Totowa, NJ (2004)

Kaiser, M.; Milbradt, A. G.; Renner, C.; Assfalg-Machleidt, I.; Groll, M.; Huber, R.; Moroder, L.: Cyclic biphenyl ether tripeptides as proteasom inhibitors. In: Peptide Revolution: Genomics, Proteomics & Therapeutics, pp. 348 - 349 (Eds. Chorev, M.; Sawyer, T. K.). American Peptide Society, Cardiff, Ca. (2004)