Publications of R. Huber

Breitenlechner, C. B.; Kairies, N. A.; Honold, K.; Scheiblich, S.; Koll, H.; Greiter, E.; Koch, S.; Schafer, W.; Huber, R.; Engh, R. A.: Crystal structures of active Src kinase domain complexes. Journal of Molecular Biology 353 (2), pp. 222 - 231 (2005)

Arolas, J. L.; Popowicz, G. M.; Bronsoms, S.; Aviles, F. X.; Huber, R.; Holak, T. A.; Ventura, S.: Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: Contribution of the fourth disulfide bond. Journal of Molecular Biology 352 (4), pp. 961 - 975 (2005)

Goettig, P.; Brandstetter, H.; Groll, M.; Göhring, W.; Konarev, P. V.; Svergun, D. I.; Huber, R.; Kim, J. S.: X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum. Journal of Biological Chemistry 280 (39), pp. 33387 - 33396 (2005)

Arolas, J. L.; Popowicz, G. M.; Lorenzo, J.; Sornmerhoff, C. P.; Huber, R.; Aviles, F. X.; Holak, T. A.: The three-dimensional structures of tick carboxypeptidase inhibitor in complex with A/B carboxypeptidases reveal a novel double-headed binding mode. Journal of Molecular Biology 350 (3), pp. 489 - 498 (2005)

Huber, R.: Proteases and their regulation - from structures to mechanisms and new concepts for intervention. FEBS Journal 272 (Suppl. Suppl. 1), p. 163 - 163 (2005)

Jauch, R.; Humm, A.; Huber, R.; Wahl, M.: Structures of Escherichia coli NAD synthetase with substrates and products reveal mechanistic rearrangements. FEBS Journal 272 (Suppl. Suppl. 1), pp. 9 - 10 (2005)

Kyrieleis, O. J. P.; Goettig, P.; Kiefersauer, R.; Huber, R.; Brandstetter, H.: Crystal structures of the tricorn interacting factor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations. Journal of Molecular Biology 349 (4), pp. 787 - 800 (2005)

Than, M. E.; Henrich, S.; Bourenkov, G. P.; Bartunik, H. D.; Huber, R.; Bode, W.: The endoproteinase furin contains two essential Ca2+ ions stabilizing its N-terminus and the unique S1 specificity pocket. Acta Crystallographica Section D-Biological Crystallography 61, pp. 505 - 512 (2005)

Wisniewska, M.; Bossenmaier, B.; Georges, G.; Hesse, F.; Dangl, M.; Kunkele, K. P.; Ioannidis, I.; Huber, R.; Engh, R. A.: The 1.1 angstrom resolution crystal structure of the p130cas SH3 domain and ramifications for ligand selectivity. Journal of Molecular Biology 347 (5), pp. 1005 - 1014 (2005)

Pal, P. P.; Bae, J. H.; Azim, M. K.; Hess, P.; Friedrich, R.; Huber, R.; Moroder, L.; Budisa, N.: Structural and spectral response of Aequorea victoria green fluorescent proteins to chromophore fluorination. Biochemistry 44 (10), pp. 3663 - 3672 (2005)

Groll, M.; Bochtler, M.; Brandstetter, H.; Clausen, T.; Huber, R.: Molecular machines for protein degradation. ChemBioChem 6 (2), pp. 222 - 256 (2005)

Theodoratou, E.; Huber, R.; Bock, A.: [NiFe]-Hydrogenase maturation endopeptidase: structure and function. Biochemical Society Transactions 33, pp. 108 - 111 (2005)

Breitenlechner, C. B.; Friebe, W. G.; Brunet, E.; Guido, W.; Graul, M.; Thomas, U.; Kunkele, K. P.; Schafer, W.; Gassel, M.; Bosseineyer, D. et al.; Huber, R.; Engh, R. A.; Masjost, B.: Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase a and mutants. Journal of Medicinal Chemistry 48 (1), pp. 163 - 170 (2005)

Einsle, O.; Niessen, H.; Abt, D. J.; Seiffert, G.; Schink, B.; Huber, R.; Messerschmidt, A.; Kroneck, P. M.: Crystallization and preliminary X-ray analysis of the tungsten-dependent acetylene hydratase from Pelobacter acetylenicus. Acta Crystallographica F61, pp. 299 - 301 (2005)

Groll, M.; Huber, R.: Purification, crystallization, and x-ray analysis of the yeast 20S proteasome. Methods in Enzymology 398, pp. 329 - 336 (2005)

Siwanowicz, I.; Popowicz, G. M.; Wisniewska, M.; Huber, R.; Kuenkele, K. P.; Lang, K.; Engh, R. A.; Holak, T. A.: Structural basis for the regulation of insulin-like growth factors by IGF binding proteins. Structure 13 (1), pp. 155 - 167 (2005)

Wenig, K.; Chatwell, L.; von Pawel-Rammingen, U.; Bjorck, L.; Huber, R.; Sondermann, P.: Structure of the streptococcal endopeptidase IdeS, a cysteine proteinase with strict specificity for IgG. Proceedings of the National Academy of Sciences of the United States of America 101 (50), pp. 17371 - 17376 (2004)

Groll, M.; Huber, R.: Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach. Biochimica et Biophysica Acta-Molecular Cell Research 1695 (1-3), pp. 33 - 44 (2004)

Baumeister, W.; Bachmair, A.; Chau, V.; Cohen, R.; Coffino, P.; DeMartino, G.; Deshaies, R.; Dohmen, J.; Emr, S.; Finley, D. et al.; Hampton, R.; Hill, C.; Hochstrasser, M.; Huber, R.; Jackson, P.; Jentsch, S.; Johnson, E.; Kwon, Y. T.; Pagano, M.; Pickart, C.; Rechsteiner, M.; Scheffner, M.; Sommer, T.; Tansey, W.; Tyers, M.; Vierstra, R.; Weissman, A.; Wilkinson, K. D.; Wolf, D.: Varshavsky's contributions. Science 306 (5700), pp. 1290 - 1292 (2004)

Baumeister, W.; Bachmair, A.; Chau, V.; Cohen, R.; Coffino, P.; DeMartino, G.; Deshaies, R.; Dohmen, J.; Emr, S.; Finley, D. et al.; Hampton, R.; Hill, C.; Hochstrasser, M.; Huber, R.; Jackson, P.; Jentsch, S.; Johnson, E.; Kwon, Y. T.; Pagano, M.; Pickart, C.; Rechsteiner, M.; Scheffner, M.; Sommer, T.; Tansey, W.; Tyers, M.; Vierstra, R.; Weissman, A.; Wilkinson, K. D.; Wolf, D.: Varshavsky's contributions. Science 306 (5700), pp. 1290 - 1292 (2004)