Infrastructure

Protein Expression

Kühner shakers for expression in E.coli
Kühner shakers for expression in E.coli

Temperature controlled room for baculovirus-infected insect cell expression
Temperature controlled room for baculovirus-infected insect cell expression
CO2-controlled incubators and shakers for mammalian cell expression
CO2-controlled incubators and shakers for mammalian cell expression

Biochemical and Functional Analyses

Various liquid chromatography systems (Äkta Primes, Purifiers and Avant)
Various liquid chromatography systems (Äkta Primes, Purifiers and Avant)
Isotope lab for 32P-labeled-nucleotide-based activity assays
Isotope lab for 32P-labeled-nucleotide-based activity assays
Dissection microscope and dedicated incubators/shakers for yeast genetics
Dissection microscope and dedicated incubators/shakers for yeast genetics

Crystallisation

Automatic setup of up to 2400 crystallization conditions with a Phoenix nanodispenser robot from Art Robbins InstrumentsOptimization of crystallization conditions using robotics
Automatic setup of up to 2400 crystallization conditions with a Phoenix nanodispenser robot from Art Robbins Instruments
Optimization of crystallization conditions using robotics


Xtal-Focus Imaging Stations (Leica/Zeiss microscopes coupled to Thermo Fischer robotic arm and carrousel)Storage of plates in vizualization systems in temperature controlled rooms (4°C, 10°C and 19°C)
Xtal-Focus Imaging Stations (Leica/Zeiss microscopes coupled to Thermo Fischer robotic arm and carrousel)
Storage of plates in vizualization systems in temperature controlled rooms (4°C, 10°C and 19°C)
In-house X-ray generator D8 Venture (Bruker), with the newly developed liquid metal jet X-ray source
In-house X-ray generator D8 Venture (Bruker), with the newly developed liquid metal jet X-ray source

 

 

 

 

 

 

 

 

 

 

D8-Venture


Biophysics

Analytical gel filtration on Waters HPLC coupled to Viskotek Static Light Scattering analyzer
Analytical gel filtration on Waters HPLC coupled to Viskotek Static Light Scattering analyzer
Isothermal calorimeter, fluorescence spectrophotometer for binding affinity estimations
Isothermal calorimeter, fluorescence spectrophotometer for binding affinity estimations
 
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