Publications

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Journal Article (14)

  1. 1.
    Journal Article
    Classen, M.; Breuer, S.; Baumeister, W.; Guckenberger, R.; Witt, S.: Force Spectroscopy of Substrate Molecules En Route to the Proteasome's Active Sites. Biophysical Journal 100 (2), pp. 489 - 497 (2011)
  2. 2.
    Journal Article
    Ruschak, A. M.; Religa, T. L.; Breuer, S.; Witt, S.; Kay, L. E.: The proteasome antechamber maintains substrates in an unfolded state. Nature 467 (7317), pp. 868 - 871 (2010)
  3. 3.
    Journal Article
    Andersson, F. I.; Tryggvesson, A.; Sharon, M.; Diemand, A. V.; Classen, M.; Best, C.; Schmidt, R.; Schelin, J.; Stanne, T. M.; Bukau, B. et al.; Robinson, C. V.; Witt, S.; Mogk, A.; Clarke, A. K.: Structure and Function of a Novel Type of ATP-dependent Clp Protease. Journal of Biological Chemistry 284 (20), pp. 13519 - 13532 (2009)
  4. 4.
    Journal Article
    Felderer, K.; Groves, M.; Diez, J.; Pohl, E.; Witt, S.: Crystallization and preliminary X-ray analysis of the Thermoplasma acidophilum 20S proteasome in complex with protein substrates. Acta Crystallographica Section F-Structural Biology and Crystallization Communications 64, pp. 899 - 902 (2008)
  5. 5.
    Journal Article
    Beuttler, M.; Breuer, S.; Witt, S.; Guckenberger, R.; Baumeister, W.: Probing of proteasome-substrate interaction with force spectroscopy. Abstracts of the 32nd FEBS Congress (2007)
  6. 6.
    Journal Article
    Breuer, S.; Huth, F.; Felderer, K.; Guckenberger, R.; Baumeister, W.; Witt, S.: Studying the translocation of substrate molecules into the 20S proteasome on ensemble and single molecule level. Abstracts of the 32nd FEBS Congress (2007)
  7. 7.
    Journal Article
    Witt, S.; Breuer, S.; Beuttler, M.; Huth, F.; Guckenberger, R.; Baumeister, W.: Hedging and nursing of the 20S proteasome: Towards understanding assembly and substrate uptake. Abstracts of the 32nd FEBS Congress (2007)
  8. 8.
    Journal Article
    Sharon, M.; Witt, S.; Glasmacher, E.; Baumeister, W.; Robinson, C. V.: Mass spectrometry reveals the missing links in the assembly pathway of the bacterial 20 S proteasome. JOURNAL OF BIOLOGICAL CHEMISTRY 282 (25), pp. 18448 - 18457 (2007)
  9. 9.
    Journal Article
    Witt, S.; Kwon, Y. D.; Sharon, M.; Felderer, K.; Beuttler, M.; Robinson, C. V.; Baumeister, W.; Jap, B. K.: Proteasome assembly triggers a switch required for active-site maturation. Structure 14 (7), pp. 1179 - 1188 (2006)
  10. 10.
    Journal Article
    Sharon, M.; Witt, S.; Felderer, K.; Rockel, B.; Baumeister, W.; Robinson, C. V.: 20S proteasomes have the potential to keep substrates in store for continual degradation. Journal of Biological Chemistry 281 (14), pp. 9569 - 9575 (2006)
  11. 11.
    Journal Article
    Schiener, J.; Witt, S.; Hayer-Hartl, M.; Guckenberger, R.: How to orient the functional GroEL-SRI mutant for atomic force microscopy investigations. Biochemical and Biophysical Research Communications 328 (2), pp. 477 - 483 (2005)
  12. 12.
    Journal Article
    Frey, H. G.; Witt, S.; Felderer, K.; Guckenberger, R.: High-resolution imaging of single fluorescent molecules with the optical near-field of a metal tip. Physical Review Letters 93 (20) (2004)
  13. 13.
    Journal Article
    Schiener, J.; Witt, S.; Stark, M.; Guckenberger, R.: Stabilized atomic force microscopy imaging in liquids using second harmonic of cantilever motion for setpoint control. Review of Scientific Instruments 75 (8), pp. 2564 - 2568 (2004)
  14. 14.
    Journal Article
    Hofmann, M.; Witt, S.; Guckenberger, R.: Probing enzyme-protein interaction with force-spectroscopy. Single Molecules 2 (2), pp. 133 - 134 (2001)

Book Chapter (1)

  1. 15.
    Book Chapter
    Witt, S.; Baumeister, W.: Proteasomes: Molecular Machines for Protein Degradation. In: Biopolymers, pp. 439 - 464 (Eds. Steinbüchel, A.; Fahnestock, S. R.). Wiley-VCH, Weinheim (2002)
 
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