Publications of T. Clausen

Journal Article (17)

1.
Journal Article
Tennstaedt, A.; Popsel, S.; Truebestein, L.; Hauske, P.; Brockmann, A.; Schmidt, N.; Irle, I.; Sacca, B.; Niemeyer, C. M.; Brandt, R. et al.; Ksiezak-Reding, H.; Tirniceriu, A. L.; Egensperger, R.; Baldi, A.; Dehmelt, L.; Kaiser, M.; Huber, R.; Clausen, T.; Ehrmann, M.: Human High Temperature Requirement Serine Protease A1 (HTRA1) Degrades Tau Protein Aggregates. Journal of Biological Chemistry 287 (25), pp. 20931 - 20941 (2012)
2.
Journal Article
Clausen, T.; Kaiser, M.; Huber, R.; Ehrmann, M.: HTRA proteases: regulated proteolysis in protein quality control. Nature Reviews Molecular Cell Biology 12 (3), pp. 152 - 162 (2011)
3.
Journal Article
Merdanovic, M.; Clausen, T.; Kaiser, M.; Huber, R.; Ehrmann, M.: Protein Quality Control in the Bacterial Periplasm. Annual Review of Microbiology 65, pp. 149 - 168 (2011)
4.
Journal Article
Krojer, T.; Sawa, J.; Huber, R.; Clausen, T.: HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues. Nature Structural & Molecular Biology 17 (7), pp. 844 - 852 (2010)
5.
Journal Article
Hasenbein, S.; Meltzer, M.; Hauske, P.; Kaiser, M.; Huber, R.; Clausen, T.; Ehrmann, M.: Conversion of a Regulatory into a Degradative Protease. Journal of Molecular Biology 397 (4), pp. 957 - 966 (2010)
6.
Journal Article
Meltzer, M.; Hasenbein, S.; Mamant, N.; Merdanovic, M.; Poepsel, S.; Hauske, P.; Kaiser, M.; Huber, R.; Krojer, T.; Clausen, T. et al.; Ehrmann, M.: Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coli. Research in Microbiology 160 (9 Sp. Iss.), pp. 660 - 666 (2009)
7.
Journal Article
Breithaupt, C.; Kurzbauer, R.; Schaller, F.; Stintzi, A.; Schaller, A.; Huber, R.; Macheroux, P.; Clausen, T.: Structural Basis of Substrate Specificity of Plant 12-Oxophytodienoate Reductases. Journal of Molecular Biology 392 (5), pp. 1266 - 1277 (2009)
8.
Journal Article
Krojer, T.; Pangerl, K.; Kurt, J.; Sawa, J.; Stingl, C.; Mechtler, K.; Huber, R.; Ehrmann, M.; Clausen, T.: Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins. Proceedings of the National Academy of Sciences of the United States of America 105 (22), pp. 7702 - 7707 (2008)
9.
Journal Article
Breithaupt, C.; Kurzbauer, R.; Lilie, H.; Schaller, A.; Strassner, J.; Huber, R.; Macheroux, P.; Clausen, T.: Crystal structure of 12-oxophytodienoate reductase 3 from tomato: Self-inhibition by dimerization. Proceedings of the National Academy of Sciences of the United States of America 103 (39), pp. 14337 - 14342 (2006)
10.
Journal Article
Groll, M.; Bochtler, M.; Brandstetter, H.; Clausen, T.; Huber, R.: Molecular machines for protein degradation. ChemBioChem 6 (2), pp. 222 - 256 (2005)
11.
Journal Article
Messerschmidt, A.; Worbs, M.; Steegborn, C.; Wahl, M. C.; Huber, R.; Laber, B.; Clausen, T.: Determinants of enzymatic specificity in the Cys-Met-metabolism PLP-dependent enzyme family: Crystal structure of cystathionine γ-lyase from yeast and intrafamiliar structure comparison. Biological Chemistry 384 (3), pp. 373 - 386 (2003)
12.
Journal Article
Kaiser, J. T.; Bruno, S.; Clausen, T.; Huber, R.; Schiaretti, F.; Mozzarelli, A.; Kessler, D.: Snapshots of the cystine lyase C-DES during catalysis - Studies in solution and in the crystalline state. Journal of Biological Chemistry 278 (1), pp. 357 - 365 (2003)
13.
Journal Article
Clausen, T.; Southan, C.; Ehrmann, M.: The HtrA family of proteases: Implications for protein composition and cell fate. Molecular Cell 10 (3), pp. 443 - 455 (2002)
14.
Journal Article
Garrido-Franco, M.; Laber, B.; Huber, R.; Clausen, T.: Enzyme-ligand complexes of pyridoxine 5 -phosphate synthase: Implications for substrate binding and catalysis. Journal of Molecular Biology 321 (4), pp. 601 - 612 (2002)
15.
Journal Article
Bertoldi, M.; Cellini, B.; Clausen, T.; Voltattorni, C. B.: Spectroscopic and kinetic analyses reveal the pyridoxal 5 '- phosphate binding mode and the catalytic features of Treponema denticola cystalysin. Biochemistry 41 (29), pp. 9153 - 9164 (2002)
16.
Journal Article
Garrido-Franco, M.; Ehlert, S.; Messerschmidt, A.; Marinkovic, S.; Huber, R.; Laber, B.; Bourenkov, G. P.; Clausen, T.: Structure and function of threonine synthase from yeast. Journal of Biological Chemistry 277 (14), pp. 12396 - 12405 (2002)
17.
Journal Article
Krojer, T.; Garrido-Franco, M.; Huber, R.; Ehrmann, M.; Clausen, T.: Crystal structure of DegP (HtrA) reveals a new protease- chaperone machine. Nature 416 (6879), pp. 455 - 459 (2002)

Book Chapter (1)

18.
Book Chapter
Bochtler, M.; Groll, M.; Brandstetter, H.; Clausen, T.; Huber, R.: Molecular machines for protein degradation. Protein Degradation. In: Protein Degradation 1, pp. 248 - 287 (Eds. Mayer, R. J.; A., C.; Rechsteiner, M.). Wiley-VCH, Weinheim (2005)
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