Publications of F. U. Hartl

Klunker, D.; Haas, B.; Hirtreiter, A.; Figueiredo, L.; Naylor, D. J.; Pfeifer, G.; Muller, V.; Deppenmeier, U.; Gottschalk, G.; Hartl, F. U. et al.; Hayer-Hartl, M.: Coexistence of group I and group II chaperonins in the archaeon Methanosarcina mazei. Journal of Biological Chemistry 278 (35), pp. 33256 - 33267 (2003)

Brychzy, A.; Rein, T.; Winklhofer, K. F.; Hartl, F. U.; Young, J. C.; Obermann, W. M. J.: Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system. EMBO Journal 22 (14), pp. 3613 - 3623 (2003)

Young, J. C.; Hartl, F. U.: A stress sensor for the bacterial periplasm. Cell 113 (1), pp. 1 - 2 (2003)

Hartl, F. U.: Chaperone-assisted protein folding in the cytosol. FASEB Journal 17 (4 Suppl. S), p. A559 - A559 (2003)

Schmidt, U.; Wochnik, G. M.; Rosenhagen, M. C.; Young, J. C.; Hartl, F. U.; Holsboer, F.; Rein, T.: Essential role of the unusual DNA-binding motif of BAG-1 for inhibition of the glucocorticoid receptor. Journal of Biological Chemistry 278 (7), pp. 4926 - 4931 (2003)

Dou, F.; Netzer, W. J.; Tanemura, K.; Li, F.; Hartl, F. U.; Takashima, A.; Gouras, G. K.; Greengard, P.; Xu, H. X.: Chaperones increase association of tau protein with microtubules. Proceedings of the National Academy of Sciences of the United States of America 100 (2), pp. 721 - 726 (2003)

Young, J. C.; Hoogenraad, N. J.; Hartl, F. U.: Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70. Cell 112 (1), pp. 41 - 50 (2003)

Sakahira, H.; Breuer, P.; Hayer-Hartl, M. K.; Hartl, F. U.: Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity. Proceedings of the National Academy of Sciences of the United States of America 99 (Suppl. 4), pp. 16412 - 16418 (2002)

Becker, T.; Hartl, F. U.; Wieland, F.: CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes. Journal of Cell Biology 158 (7), pp. 1277 - 1285 (2002)

Ashcroft, A. E.; Brinker, A.; Coyle, J. E.; Weber, F.; Kaiser, M.; Moroder, L.; Parsons, M. R.; Jager, J.; Hartl, F. U.; Hayer-Hartl, M. et al.; Radford, S. E.: Structural plasticity and noncovalent substrate binding in the GroEL apical domain - A study using electrospray ionization mass spectrometry and fluorescence binding studies. Journal of Biological Chemistry 277 (36), pp. 33115 - 33126 (2002)

Sondermann, H.; Ho, A. K.; Listenberger, L. L.; Siegers, K.; Moarefi, I.; Wente, S. R.; Hartl, F. U.; Young, J. C.: Prediction of novel bag-1 homologs based on structure/function analysis identifies Snl1p as an Hsp70 co-chaperone in Saccharomyces cerevisiae. Journal of Biological Chemistry 277 (36), pp. 33220 - 33227 (2002)

Young, J. C.; Hartl, F. U.: Chaperones and transcriptional regulation by nuclear receptors. Nature Structural Biology 9 (9), pp. 640 - 642 (2002)

Brinker, A.; Scheufler, C.; von der Mülbe, F.; Fleckenstein, B.; Herrmann, C.; Jung, G.; Moarefi, I.; Hartl, F. U.: Ligand discrimination by TPR domains - Relevance and selectivity of EEVD-recognition in Hsp70 x Hop x Hsp90 complexes. Journal of Biological Chemistry 277 (22), pp. 19265 - 19275 (2002)

Sittler, A.; Lurz, R.; Lueder, G.; Priller, J.; Lehrach, H.; Hayer-Hartl, M.; Hartl, U.; Wanker, E. E.: Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease. European Journal of Human Genetics 10 (Suppl. Suppl. 1), p. 270 - 270 (2002)

Hartl, F. U.; Hayer-Hartl, M.: Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 295 (5561), pp. 1852 - 1858 (2002)

Barral, J. M.; Hutagalung, A. H.; Brinker, A.; Hartl, F. U.; Epstein, H. F.: Role of the myosin assembly protein UNC-45 as a molecular chaperone for myosin. Science 295 (5555), pp. 669 - 671 (2002)

Brinker, A.; Pfeifer, G.; Kerner, M.J.; Naylor, D.J.; Hartl, F. U.; Hayer-Hartl, M. K.: Dual Function of Protein Confinement in Chaperonin-assisted Protein Folding. Cell 107 (2), pp. 223 - 233 (2001)

Engel, A.; Hayerhartl, M. K.; Goldie, K. N.; Pfeifer, G.; Hegerl, R.; Müller, S.; Dasilva, A. C. R.; Baumeister, W.; Hartl, F. U.: Functional significance of symmetrical versus asymmetrical groel-groes chaperonin complexes. Science 269 (5225), pp. 832 - 836 (1995)

Waldmann, T.; Nimmesgern, E.; Nitsch, M.; Peters, J.; Pfeifer, G.; Müller, S.; Kellermann, J.; Engel, A.; Hartl, F. U.; Baumeister, W.: The thermosome of thermoplasma acidophilum and its relationship to the eukaryotic chaperonin tric. European Journal of Biochemistry 227 (3), pp. 848 - 856 (1995)

Langer, T.; Pfeifer, G.; Martin, J.; Baumeister, W.; Hartl, F. U.: Chaperonin-mediated protein folding: GroES binds to one end of the GroEL cylinder, which accommodates the protein substrate within its central cavity. EMBO Journal. 11 (13), pp. 4757 - 4765 (1992)