Search results

Journal Article (21)

1. 1.
   MPG.PuRe

   DOI
   Journal Article

   van Well, E. M.; Bader, V.; Patra, M.; Sanchez-Vicente, A.; Meschede, J.; Furthmann, N.; Schnack, C.; Blusch, A.; Longworth, J.; Petrasch-Parwez, E. et al.; Mori, K.; Arzberger, T.; Truembach, D.; Angersbach, L.; Showkat, C.; Sehr, D. A.; Berlemann, L. A.; Goldmann, P.; Clement, A. M.; Behl, C.; Woerner, A. C.; Saft, C.; Wurst, W.; Haass, C.; Ellrichmann, G.; Gold, R.; Dittmar, G.; Hipp, M. S.; Hartl, F. U.; Tatzelt, J.; Winklhofer, K. F.: A protein quality control pathway regulated by linear ubiquitination. EMBO Journal 38 (9) (2019)
2. 2.
   MPG.PuRe

   DOI

   publisher-version
   Journal Article

   Vincenz-Donnelly, L.; Holthusen, H.; Körner, R.; Hansen, E. C.; Presto, J.; Johansson, J.; Sawarkar, R.; Hartl, F. U.; Hipp, M. S.: High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins. The EMBO Journal 37 (3), pp. 337 - 350 (2018)
3. 3.
   MPG.PuRe

   DOI

   publisher-version
   Journal Article

   Gruber, A.; Hornburg, D.; Antonin, M.; Krahmer, N.; Collado, J.; Schaffer, M.; Zubaite, G.; Luechtenborg, C.; Sachsenheimer, T.; Bruegger, B. et al.; Mann, M.; Baumeister, W.; Hartl, F. U.; Hipp, M. S.; Fernandez-Busnadiego, R.: Molecular and structural architecture of polyQ aggregates in yeast. Proceedings of the National Academy of Sciences of the United States of America 115 (15), pp. E3446 - E3453 (2018)
4. 4.
   MPG.PuRe

   DOI
   Journal Article

   Guo, Q.; Lehmer, C.; Martinez Sanchez, A.; Rudack, T.; Beck, F.; Hartmann, H.; Perez-Berlanga, M.; Frottin, F.; Hipp, M. S.; Hartl, F. U. et al.; Edbauer, D.; Baumeister, W.; Fernandez-Busnadiego, R.: In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell 172 (4), pp. 696 - 705.e12 (2018)
5. 5.
   MPG.PuRe

   DOI

   publisher-version
   Journal Article

   Hosp, F.; Gutiérrez-Ángel, S.; Schaefer, M. H.; Cox, J.; Meissner, F.; Hipp, M. S.; Hartl, F. U.; Klein, R.; Dudanova, I.; Mann, M.: Spatiotemporal Proteomic Profiling of Huntington’s Disease Inclusions Reveals Widespread Loss of Protein Function. Cell Reports 21 (8) (2017)
6. 6.
   MPG.PuRe

   DOI
   Journal Article

   Bäuerlein, F. J. B.; Saha, I.; Mishra, A.; Kalemanov, M.; Martinez-Sanchez, A.; Klein, R.; Dudanova, I.; Hipp, M. S.; Hartl, F. U.; Baumeister, W. et al.; Fernandez-Busnadiego, R.: In Situ Architecture and Cellular Interactions of PolyQ Inclusions. Cell 171 (1) (2017)
7. 7.
   MPG.PuRe

   DOI
   Journal Article

   De Smet, F.; Rubio, M. S.; Hompes, D.; Naus, E.; De Baets, G.; Langenberg, T.; Hipp, M. S.; Houben, B.; Claes, F.; Charbonneau, S. et al.; Blanco, J. D.; Plaisance, S.; Ramkissoon, S.; Ramkissoon, L.; Simons, C.; van den Brandt, P.; Weijenberg, M.; Van England, M.; Lambrechts, S.; Amant, F.; D'Hoore, A.; Ligon, K. L.; Sagaert, X.; Schymkowitz, J.; Rousseau, F.: Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation. Journal of Pathology: an Official Journal of the Pathological Society 242 (1), pp. 24 - 38 (2017)
8. 8.
   MPG.PuRe

   DOI
   Journal Article

   Vincenz-Donnelly, L.; Hipp, M. S.: The endoplasmic reticulum: A hub of protein quality control in health and disease. Free Radical Biology and Medicine 108, pp. 383 - 393 (2017)
9. 9.
   MPG.PuRe

   pre-print
   Journal Article

   Woerner, A. C.; Frottin, F.; Hornburg, D.; Feng, L. R.; Meissner, F.; Patra, M.; Tatzelt, J.; Mann, M.; Winklhofer, K. F.; Hartl, F. U. et al.; Hipp, M. S.: Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA. Science 351 (6269), pp. 173 - 176 (2016)
10. 10.
    MPG.PuRe

    DOI
    Journal Article

    Landreh, M.; Sawaya, M. R.; Hipp, M. S.; Eisenberg, D. S.; Wuthrich, K.; Hartl, F. U.: The formation, function and regulation of amyloids: insights from structural biology [Review]. Journal of Internal Medicine 280 (2), pp. 164 - 176 (2016)
11. 11.
    MPG.PuRe
    Journal Article

    Kirstein, J.; Morito, D.; Kakihana, T.; Sugihara, M.; Minnen, A.; Hipp, M. S.; Nussbaum-Krammer, C.; Kasturi, P.; Hartl, F. U.; Nagata, K. et al.; Morimoto, R. I.: Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments. EMBO JOURNAL 34 (18), pp. 2334 - 2349 (2015)
12. 12.
    MPG.PuRe

    DOI

    pre-print
    Journal Article

    Hipp, M. S.; Park, S.-H.; Hartl, F. U.: Proteostasis impairment in protein-misfolding and -aggregation diseases. Trends in Cell Biology 24 (9), pp. 506 - 514 (2014)
13. 13.
    MPG.PuRe

    DOI

    Full
    Journal Article

    Ripaud, L.; Chumakova, V.; Antonin, M.; Hastie, A. R.; Pinkert, S.; Körner, R.; Ruff, K. M.; Pappu, R. V.; Hornburg, D.; Mann, M. et al.; Hartl, F.-U.; Hipp, M. S.: Overexpression of Q-rich prion-like proteins suppresses polyQ cytotoxicity and alters the polyQ interactome. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111 (51), pp. 18219 - 18224 (2014)
14. 14.
    MPG.PuRe

    DOI
    Journal Article

    Park, S.-H.; Kukushkin, Y.; Gupta, R.; Chen, T.; Konagai, A.; Hipp, M. S.; Hayer-Hartl, M.; Hartl, F. U.: PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone. Cell 154 (1), pp. 134 - 145 (2013)
15. 15.
    MPG.PuRe

    DOI
    Journal Article

    Hipp, M. S.; Patel, C. N.; Bersuker, K.; Riley, B. E.; Kaiser, S. E.; Shaler, T. A.; Brandeis, M.; Kopito, R. R.: Indirect inhibition of 26S proteasome activity in a cellular model of Huntington's disease. J Cell Biol 196 (5), pp. 573 - 87 (2012)
16. 16.
    MPG.PuRe

    DOI
    Journal Article

    Hipp, M. S.; Bersuker, K.; Kopito, R. R.: Live-cell imaging of ubiquitin-proteasome system function. Methods Mol Biol 832, pp. 463 - 72 (2012)
17. 17.
    MPG.PuRe

    DOI
    Journal Article

    Riley, B. E.; Kaiser, S. E.; Shaler, T. A.; Ng, A. C.; Hara, T.; Hipp, M. S.; Lage, K.; Xavier, R. J.; Ryu, K. Y.; Taguchi, K. et al.; Yamamoto, M.; Tanaka, K.; Mizushima, N.; Komatsu, M.; Kopito, R. R.: Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection. J Cell Biol 191 (3), pp. 537 - 52 (2010)
18. 18.
    MPG.PuRe

    DOI
    Journal Article

    Schmidtke, G.; Kalveram, B.; Weber, E.; Bochtler, P.; Lukasiak, S.; Hipp, M. S.; Groettrup, M.: The UBA domains of NUB1L are required for binding but not for accelerated degradation of the ubiquitin-like modifier FAT10. J Biol Chem 281 (29), pp. 20045 - 54 (2006)
19. 19.
    MPG.PuRe

    DOI
    Journal Article

    Hipp, M. S.; Kalveram, B.; Raasi, S.; Groettrup, M.; Schmidtke, G.: FAT10, a ubiquitin-independent signal for proteasomal degradation. Mol Cell Biol 25 (9), pp. 3483 - 91 (2005)
20. 20.
    MPG.PuRe

    DOI
    Journal Article

    Hipp, M. S.; Raasi, S.; Groettrup, M.; Schmidtke, G.: NEDD8 ultimate buster-1L interacts with the ubiquitin-like protein FAT10 and accelerates its degradation. J Biol Chem 279 (16), pp. 16503 - 10 (2004)