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Journal Article (20)
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1.Journal ArticleHigh capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins. The EMBO Journal 37 (3), pp. 337 - 350 (2018)
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2.Journal ArticleMolecular and structural architecture of polyQ aggregates in yeast. Proceedings of the National Academy of Sciences of the United States of America 115 (15), pp. E3446 - E3453 (2018)
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3.Journal ArticleIn Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell 172 (4), pp. 696 - 705.e12 (2018)
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4.Journal ArticleSpatiotemporal Proteomic Profiling of Huntington’s Disease Inclusions Reveals Widespread Loss of Protein Function. Cell Reports (2017)
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5.Journal ArticleIn Situ Architecture and Cellular Interactions of PolyQ Inclusions. Cell (2017)
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6.Journal ArticleNuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation. Journal of Pathology: an Official Journal of the Pathological Society 242 (1), pp. 24 - 38 (2017)
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7.Journal ArticleThe endoplasmic reticulum: A hub of protein quality control in health and disease. Free Radical Biology and Medicine 108, pp. 383 - 393 (2017)
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8.Journal ArticleCytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA. Science 351 (6269), pp. 173 - 176 (2016)
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9.Journal ArticleThe formation, function and regulation of amyloids: insights from structural biology [Review]. Journal of Internal Medicine 280 (2), pp. 164 - 176 (2016)
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10.Journal ArticleProteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments. EMBO JOURNAL 34 (18), pp. 2334 - 2349 (2015)
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11.Journal ArticleProteostasis impairment in protein-misfolding and -aggregation diseases. Trends in Cell Biology 24 (9), pp. 506 - 514 (2014)
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12.Journal ArticleOverexpression of Q-rich prion-like proteins suppresses polyQ cytotoxicity and alters the polyQ interactome. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111 (51), pp. 18219 - 18224 (2014)
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13.Journal ArticlePolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone. Cell 154 (1), pp. 134 - 145 (2013)
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14.Journal ArticleIndirect inhibition of 26S proteasome activity in a cellular model of Huntington's disease. J Cell Biol 196 (5), pp. 573 - 87 (2012)
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15.Journal ArticleLive-cell imaging of ubiquitin-proteasome system function. Methods Mol Biol 832, pp. 463 - 72 (2012)
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16.Journal ArticleUbiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection. J Cell Biol 191 (3), pp. 537 - 52 (2010)
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17.Journal ArticleThe UBA domains of NUB1L are required for binding but not for accelerated degradation of the ubiquitin-like modifier FAT10. J Biol Chem 281 (29), pp. 20045 - 54 (2006)
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18.Journal ArticleFAT10, a ubiquitin-independent signal for proteasomal degradation. Mol Cell Biol 25 (9), pp. 3483 - 91 (2005)
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19.Journal ArticleNEDD8 ultimate buster-1L interacts with the ubiquitin-like protein FAT10 and accelerates its degradation. J Biol Chem 279 (16), pp. 16503 - 10 (2004)
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20.Journal ArticleProteasome inhibition leads to NF-kappaB-independent IL-8 transactivation in human endothelial cells through induction of AP-1. Eur J Immunol 32 (8), pp. 2208 - 17 (2002)
