Journal Article (185)

41.
Journal Article
Vincenz-Donnelly, L.; Holthusen, H.; Körner, R.; Hansen, E. C.; Presto, J.; Johansson, J.; Sawarkar, R.; Hartl, F. U.; Hipp, M. S.: High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins. The EMBO Journal 37 (3), pp. 337 - 350 (2018)
42.
Journal Article
Klaips, C. L.; Jayaraj, G. G.; Hartl, F. U.: Pathways of cellular proteostasis in aging and disease. The Journal of Cell Biology: JCB 217 (1), pp. 51 - 63 (2018)
43.
Journal Article
Balchin, D.; Milicic, G.; Strauss, M.; Hayer-Hartl, M.; Hartl, F. U.: Pathway of Actin Folding Directed by the Eukaryotic Chaperonin TRiC. Cell 174 (6), pp. 1507 - 1521.e16 (2018)
44.
Journal Article
Gruber, A.; Hornburg, D.; Antonin, M.; Krahmer, N.; Collado, J.; Schaffer, M.; Zubaite, G.; Luechtenborg, C.; Sachsenheimer, T.; Bruegger, B. et al.; Mann, M.; Baumeister, W.; Hartl, F. U.; Hipp, M. S.; Fernandez-Busnadiego, R.: Molecular and structural architecture of polyQ aggregates in yeast. Proceedings of the National Academy of Sciences of the United States of America 115 (15), pp. E3446 - E3453 (2018)
45.
Journal Article
Guo, Q.; Lehmer, C.; Martinez Sanchez, A.; Rudack, T.; Beck, F.; Hartmann, H.; Perez-Berlanga, M.; Frottin, F.; Hipp, M. S.; Hartl, F. U. et al.; Edbauer, D.; Baumeister, W.; Fernandez-Busnadiego, R.: In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell 172 (4), pp. 696 - 705.e12 (2018)
46.
Journal Article
Yan, X.; Shi, Q.; Bracher, A.; Milicic, G.; Singh, A. K.; Hartl, F. U.; Hayer-Hartl, M.: GroEL Ring Separation and Exchange in the Chaperonin Reaction. Cell 172 (3), pp. 605 - 617.e11 (2018)
47.
Journal Article
Aigner, H.; Wilson, R. H.; Bracher, A.; Calisse, L.; Bhat, J. Y.; Hartl, F. U.; Hayer-Hartl, M.: Plant RuBisCo assembly in E. coli with five chloroplast chaperones including BSD2. Science 358 (6368), pp. 1272 - 1278 (2017)
48.
Journal Article
Hosp, F.; Gutiérrez-Ángel, S.; Schaefer, M. H.; Cox, J.; Meissner, F.; Hipp, M. S.; Hartl, F. U.; Klein, R.; Dudanova, I.; Mann, M.: Spatiotemporal Proteomic Profiling of Huntington’s Disease Inclusions Reveals Widespread Loss of Protein Function. Cell Reports 21 (8), pp. 2291 - 2303 (2017)
49.
Journal Article
Hartl, F. U.: Unfolding the chaperone story. Molecular Biology of the Cell 28 (22), pp. 2919 - 2923 (2017)
50.
Journal Article
Bäuerlein, F. J. B.; Saha, I.; Mishra, A.; Kalemanov, M.; Martinez-Sanchez, A.; Klein, R.; Dudanova, I.; Hipp, M. S.; Hartl, F. U.; Baumeister, W. et al.; Fernandez-Busnadiego, R.: In Situ Architecture and Cellular Interactions of PolyQ Inclusions. Cell 171 (1), e10, pp. 179 - 187.e10 (2017)
51.
Journal Article
Bhat, J. Y.; Milicic, G.; Thieulin-Pardo, G.; Bracher, A.; Maxwell, A.; Ciniawsky, S.; Mueller-Cajar, O.; Engen, J. R.; Hartl, F. U.; Wendler, P. et al.; Hayer-Hartl, M.: Mechanism of Enzyme Repair by the AAA(+) Chaperone Rubisco Activase. Molecular Cell 67 (5), pp. 744 - 756.e6 (2017)
52.
Journal Article
Hartl, F. U.: Protein Misfolding Diseases. Annual Review of Biochemistry 86, pp. 21 - 26 (2017)
53.
Journal Article
Izawa, T.; Park, S.-H.; Zhao, L.; Hartl, F. U.; Neupert, W.: Cytosolic Protein Vms1 Links Ribosome Quality Control to Mitochondrial and Cellular Homeostasis. Cell 171 (4), pp. 890 - 903 (2017)
54.
Journal Article
Hartl, F.-U.: Susan Lee Lindquist (1949-2016)-pioneer in the study of cellular protein folding and disease. The EMBO Journal 35 (24), pp. 2626 - 2627 (2016)
55.
Journal Article
Kim, Y. E.; Hosp, F.; Frottin, F.; Ge, H.; Mann, M.; Hayer-Hartl, M.; Hartl, F. U.: Soluble Oligomers of PolyQ-Expanded Huntingtin Target a Multiplicity of Key Cellular Factors. Molecular Cell 63 (6), pp. 951 - 964 (2016)
56.
Journal Article
Balchin, D.; Hayer-Hartl, M.; Hartl, F. U.: In vivo aspects of protein folding and quality control. Science 353 (6294), aac4354 (2016)
57.
Journal Article
Woerner, A. C.; Frottin, F.; Hornburg, D.; Feng, L. R.; Meissner, F.; Patra, M.; Tatzelt, J.; Mann, M.; Winklhofer, K. F.; Hartl, F. U. et al.; Hipp, M. S.: Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA. Science 351 (6269), pp. 173 - 176 (2016)
58.
Journal Article
Choe, Y.-J.; Park, S.-H.; Hassemer, T.; Körner, R.; Vincenz-Donnelly, L.; Hayer-Hartl, M.; Hartl, F. U.: Failure of RQC machinery causes protein aggregation and proteotoxic stress. Nature 531 (7593), pp. 191 - 195 (2016)
59.
Journal Article
Hartl, F. U.: Cellular Homeostasis and Aging. Annual Review of Biochemistry 85, pp. 1 - 4 (2016)
60.
Journal Article
Hayer-Hartl, M.; Bracher, A.; Hartl, F. U.: The GroEL-GroES Chaperonin Machine: A Nano-Cage for Protein Folding. Trends in Biochemical Sciences: TIBS / International Union of Biochemistry and Molecular Biology. 41 (1; Special Issue: 40 Years of TiBS), pp. 62 - 76 (2016)
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