Philipp Erdmann

Project Group Leader
Research Department Molecular Structural Biology
+49 89 8578-2653

Curriculum Vitae Philipp S. Erdmann

Email: erdmann@biochem.mpg.de


PERSONAL DETAILS


Date of Birth:                January 19, 1984                                                             Nationality:       German
Birth name:       Stawski Place of birth:       Würzburg, Germany

EDUCATION AND RESEARCH EXPERIENCE


Since 2016
Project Group Leader Subcellular Localization and Correlative FIB
at Max Planck Institute of Biochemistry, Martinsried, Germany
Molecular Structural Biology
Department Prof. Wolfgang Baumeister/ Jürgen Plitzko

Research Interest: Refining methods for subcellular protein localization and 3D correlative cryo-focused ion beam (FIB) milling and cryo-electron tomography (cryo-ET). Addressing biological questions pertaining to phase separation as found in nucleolar organization, ribosome biogenesis and autophagy by in situ cryo-ET. Developing protein nanostructures as tags and markers for cryo-ET.
2013 - 2015
Postdoctoral Fellow
Massachusetts Institute of Technology, USA
Research Advisors: Prof. Alice Y. Ting and Prof. M. Bathe

Research topic: Imaging of synaptic proteins by stochastic optical reconstruction (STORM) and electron microscopy (EM).
12.12.2012
DR. rer. nat. (PhD) summa cum laude
2008 - 2013
PhD in Synthetic Organic Chemistry and Chemical Biology
Research Advisor: Prof Dirk Trauner
Ludwig Maximilian University of Munich (LMU), Germany

Research topic: Chemical optogenetics: Controlling endogenous ionotropic glutamate receptors (iGluRs) with light
2008
Diploma Thesis
Julius Maximilian University of Würzburg, Germany
Research advisor: Prof. Gerhard Bringmann

Research topic: Studies toward the selective synthesis of Ancistrocladinum A by an atroposelective Bischler-Napieralski reaction
2003 - 2008
Studies in Organic Chemistry, Inorganic Chemistry, Physical Chemistry, Physics
Julius Maximilian University of Würzburg, Germany
2007
Study abroad
University of Wyoming, Laramie, WY
Research advisor: Prof. Jan Kubelka

Research topic: The temperature dependence of amide I intensities of peptides in solution
1994 - 2003
Wilhelm Conrad Röntgen Gymnasium Würzburg, Germany
1990 - 1994
Johannes-Keppler Grundschule Würzburg, Germany

 

PUBLICATIONS


* corresponding author; ° co-1st author

 1.     S. Tacke°, P. S. Erdmann°, Z. Wang, S. Klumpe, M. Grange, R. Kříž, M. Dolník, J. M. Plitzko, S. Raunser: A streamlined workflow for automated cryo focused ion beam milling. submitted (bioRxiv: https://doi.org/10.1101/2020.02.24.963033 ).

 2.     F. Wilfling*, C.-W. Lee, P. S. Erdmann*, W. Baumeister*, and S. Jentsch: Selective autophagy degrades aberrant endocytic assemblies. submitted.

 3.     L. E. Wong, A. Bhatt, P. S. Erdmann, Z. Hou, J. Maier, S. Pirkuliyeva et al.: Tripartite phase separation of signal effectors with vesicles priming B cell responsiveness. Nat Commun.11, (2020).

 4.     M. Le Guennec, N. Klena, D. Gambarotto, M. H. Laporte, A.-M. Tassin, H. van den Hoek, P. S. Erdmann, M. Schaffer, L. Kovacik, S. Borgers, K. N. Goldie, H. Stahlberg, M. Bornens, J. Azimzadeh, B. D. Engel, V. Hamel, P. Guichard: A helical inner scaffold provides a structural basis for centriole cohesion. Science Advances 6, (2020).

 5.     F. Sigmund, C. Massner, P. S. Erdmann, A. Stelzl, H. Rolbieski, M. Desai, et al.: Bacterial encapsulins as orthogonal compartments for mammalian cell engineering. Nat. Commun. 9, (2018).

 6.     P. S. Erdmann , J. M. Plitzko, and W. Baumeister: Addressing cellular compart-mentalization by in situ cryo-electron tomography. Curr. Opin. Colloid Interface Sci. 34, 89–99 (2018).

 7.     L. Laprell, K. Hüll, P. S. Stawski, C. Schön, S. Michalakis, M. Biel et al.: Restoring Light Sensitivity in Blind Retinae Using a Photochromic AMPA Receptor Agonist. ACS Chem. Neurosci. 7, 15–20 (2016).

 8.     K. H. Loh, P. S. Stawski, A. S. Draycott, N. D. Udeshi, E. K. Lehrman, D. K. Wilton et al.: Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts. Cell 166, 1295–1307 (2016).

 9.     R. Seupel, B. Hertlein-Amslinger, T. Gulder, P. S. Stawski, M. Kaiser, R. Brun et al.: Directed Synthesis of All Four Pure Stereoisomers of the N,C-Coupled Naphthylisoquinoline Alkaloid Ancistrocladinium A. Org. Lett. 18, 6508–6511 (2016).

10.    M. S. Lee, C. R. Glassman, N. R. Deshpande, H. B. Badgandi, H. L. Parrish, C. Uttamapinant, P. S. Stawski et al.: A Mechanical Switch Couples T Cell Receptor Triggering to the Cytoplasmic Juxtamembrane Regions of CD3ζζ. Immunity 43, 227–39 (2015).

11.    P. S. Stawski and M. Sumser:  Photocontrol of AMPA receptors with a photochromic ligand. Methods Mol. Biol. 1148, 69–76 (2014).

12.    J. Levitz, C. Pantoja, B. Gaub, H. Janovjak, A. Reiner, A. Hoagland, D. Schoppik, B. Kane, P. S. Stawski et al.: Optical control of metabotropic glutamate receptors. Nat. Neurosci. 16, 507–16 (2013). 

13.    P. S. Stawski , M. Sumser, and D. Trauner: A Photochromic Agonist of AMPA Receptors. Angew. Chemie Int. Ed. 51, 5748–5751 (2012).

14.    P. S. Stawski , H. Janovjak, and D. Trauner: Pharmacology of ionotropic glutamate receptors: A structural perspective. Bioorg. Med. Chem. 18, 7759–7772 (2010).

15.    L. Ackels, P. S. Stawski, K. E. Amunson, and J. Kubelka: On the temperature dependence of amide I intensities of peptides in solution. Vib. Spectrosc. 50, 2–9 (2009).

Book Chapters


1.     P. S. Erdmann, S. Klumpe, J. M. Plitzko: Kapitel 23 “Elektronenmikroskopie” in Bioanalytik, Edts. F. Lottespeich, J. W. Engels, Springer (2020).

AWARDS AND FELLOWSHIPS


2015 – 2016
Feodor Lynen Returners Fellowship from the Alexander von Humboldt Foundation

2014 – 2015
Feodor Lynen Fellowship from the Alexander von Humboldt Foundation

2013 – 2014
Postdoctoral Fellow of the Simons Center for the Social Brain (Simons Foundation, MIT)

2013
Römer Preis for an outstanding PhD thesis awarded by the Klaus Römer Foundation (LMU, Munich)

2009 – 2012
Kekulé PhD Scholarship from the Stipendienfonds der Chemischen Industrie

2008
Faculty Award for an outstanding diploma thesis awarded by the Chemical and Pharmaceutical Faculty of the University of Würzburg

LANGUAGES


German (native speaker), English (fluent)

 

Go to Editor View