Dr. Zuzana Storchova
Group Leader
Phone:+49 89 8578 - 3145

MPI of Biochemistry, Am Klopferspitz 18, 82152 Martinsried

Maintenance of Genome Stability

Research Group "Maintenance of Genome Stability"

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Our research group is moving to the University of Kaiserslautern. The laboratory in Munich will be closed by end of 2016.


We recently published following articles:

Kuznetsova AY, Seget K, Moeller GK, de Pagter MS, de Roos JADM, Dürrbaum M, Kuffer C, Müller S, Zaman GJR, Kloosterman WP, Storchová Z (2015) Whole genome doubling promotes chromosomal instability, tolerance of mitotic errors and multidrug resistance, Cell Cycle 14: 2810-20.


Donnelly N, Passerini V, Dürrbaum M, Stingele S, Storchová Z (2014) HSF1 deficiency and impaired HSP90-dependent protein folding are hallmarks of aneuploid human cells, EMBO Journal 33:2374-87.


Peplowska K, Wallek AU, Storchová Z (2014) Sgo1 Regulates both Condensin and Ipl1/Aurora B to Promote Chromosome Biorientation, PLoS Genet. 10: e1004411.


Dürrbaum M, Kuznetsova AY, Passerini V, Stingele S, Stoehr G, Storchová Z (2014) Unique features of the transcriptional response to model aneuploidy in human cells. BMC Genomics 2014, 15:139 - 52.


and reviews:

Donnelly N, Storchová Z (2015) Causes and consequences of protein folding stress in aneuploid cells, Cell Cycle, 14:4, 495-501.


Donnelly N, Storchová Z (2015) Aneuploidy and proteotoxic stress in cancer, Molecular & Cellular Oncology, 2: e976491


Dürrbaum M, Storchová Z (2015) Effects of aneuploidy on gene expression: implications for cancer, FEBS J. doi: 10.1111/febs.13591.




Current funding:


Max Planck Society


Deutsche Forschungsgemeinschaft (Project "Maintenance of proteostasis in human aneuploid cell lines")


Center of Integrated Protein Science - Cluster of Excellence


International Training Network – Marie Curie Action PloidyNet

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