Leon Babl
PhD Student
Leon is fascinated by the biochemical variety proteins have to offer. After studying enzyme kinetics in his B.Sc. at the University of Regensburg, he moved to the UK and got interested by protein self-organization. In his master, he investigated the propensity of proteins to form liquid-like entities and studied their biochemistry. To combine his interests in enzyme kinetics and protein self-organization for his PhD, he moved to Munich and is now studying the liquid-liquid phase separation of bacterial enzymes. Besides proteins, he has great interest in all kinds of alpine-style adventures!
Research Interests
Phase Separation, Self-Organization, Protein Biochemistry
Awards
| 2016 - 2019 | Member of the German Academic Scholarship Foundation (Studienstiftung des deutschen Volkes) |
Publications
Kohyama, S.*, Frohn, B. P.*, Babl, L., Schwille, P.
(*contributed equally)
Designing a protein with emergent function by combined in silico, in vitro and in vivo screening
bioRxiv (2023) doi.org/10.1101/2023.02.16.528840
Babl, L., Giacomelli, G., Ramm, B., Gelmroth, A.-K., Bramkamp, M., and Schwille,P.
Ctp-controlled liquid–liquid phase separation of parB.
Journal of molecular biology (2022)
Babl, L., Merino-Salomón, A., Kanwa, N., Schwille, P.
Membrane mediated phase separation of the bacterial nucleoid occlusion protein Noc.
Scientific Reports (2022)
Crabtree, M. D., Holland, J., Kompella, P., Babl, L., Turner, N., Baldwin, A. J., and Nott, T. J.
Repulsive electrostatic interactions modulate dense and dilute phase properties of biomolecular condensates.
bioRxiv (2021)
Merino-Salomon*, A., Babl*, L., and Schwille, P.
Self-organized protein patterns: The minCDE and parABS systems.
Current Opinion in Cell Biology (2021)
*shared first-author
Peterhoff, D., Glück, V., Vogel, M., Schuster, P., Schütz, A., Neubert, P., Albert,V., Frisch, S., Kiessling, M., Pervan, P., et al.
A highly specific and sensitive serological assay detects sars-cov-2 antibody levels in covid-19 patients that correlate with neutralization.
Infection (2021)
Stasi, M., Monferrer, A., Babl, L., Wunnava, S., Dirscherl, C.F., Braun, D., Schwille, P., Dietz, H., Boekhoven, J. Regulating DNA-Hybridization Using a Chemically Fueled Reaction Cycle.
JACS (2022)