Thomas Wollert receives Eppendorf Award for Young European Investigators

April 20, 2015
With the Eppendorf Young Investigator Award, the Eppendorf AG honors outstanding work in biomedical research in collaboration with the scientific journal Nature. Thomas Wollert, group leader at the Max Planck Institute of Biochemistry in Martinsried near Munich, Germany, was selected by an independent Award Jury for his groundbreaking studies to reveal how fundamental cellular transport processes are coordinated at a molecular level. The biochemist receives the 20,000 Euro prize for identifying mechanisms that drive intracellular recycling pathways. “The award honors our efforts to study complex biological transport mechanisms in cells by reconstituting them from purified components in the test tube,” explains Thomas Wollert. “The results of our challenging studies provide the basis for the development of new therapies to treat human diseases including cancer and neurodegeneration.” The official award ceremony with (invited) representatives from science, economy, and media will take place at the EMBL Advanced Training Centre in Heidelberg, Germany, on June 25, 2015.

How do cells get rid of their waste?

The cells of our body face similar challenges as we do: without efficient waste disposal systems heaps of trash will accumulate over time. Human cells therefore rely on specific mechanisms to pick up cellular waste such as superfluous or damaged organelles and to deliver them to recycling facilities. Diminished performance of this cellular recycling system may cause severe disorders including Alzheimer´s disease or cancer. The research of Thomas Wollert and his team focuses on autophagy, which represents an important recycling system of the cell. During autophagy, cellular waste is captured and subsequently delivered to specialized recycling facilities, called lysosomes. Thus, autophagy protects the cell from accumulating cell debris. “The Eppendorf-Award honors our efforts to understand cellular transport mechanisms at a molecular scale,” says Thomas Wollert, group leader at the MPI of Biochemistry since 2010. “Our findings might provide the basis for the development of new therapies against cancer or neurodegenerative diseases such as Alzheimer.”

With the Eppendorf Young Investigator Award, which was established in 1995, the Eppendorf AG honors in partnership with the scientific journal Nature outstanding work in biomedical research to support young scientists in Europe up to on age of 35. The Award winner is selected by an independent committee composed of chairman Prof. Reinhard Jahn (Max Planck Institute for Biophysical Chemistry, Göttingen, Germany), Prof. Dieter Häussinger (Clinic for Gastroenterology, Hepatology and Infectiology, Düsseldorf, Germany), Prof. Maria Leptin (EMBO, Heidelberg, Germany), and Prof. Martin J. Lohse (Institute for Pharmacology and Toxicology, University of Würzburg, Germany). The award is endowed with 20,000 €.

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