Prof. Dr.  Matthias Mann

Prof. Dr. Matthias Mann


Curriculum vitae – Matthias Mann                                    

NAME                    Matthias Mann

TITLE                    Prof. Dr. rer. nat. Dr. Dr. h.c.

POSITION TITLE      Director
                            Department of Proteomics and Signal Transduction
                            Max-Planck-Institute of Biochemistry

BIRTHDATE             10/10/1959

CONTACT DETAILS   Max Planck Institute of Biochemistry
                            Am Klopferspitz 18
                            82152 Martinsried (near Munich), Germany

                            Tel: +49 89 8578 2557
                            Fax: +49 89 8578 2219




1982 Georg August Universität Göttingen; B.A.; Physics, Mathematics
1984 Georg August Universität Göttingen; Master’s Degree; Physics
1988 Yale University; Ph.D.; Chemical Engineering

Professional Experience:

1989–1992 Post doctoral fellow and later Senior Scientist in the Department of Molecular Biology, University of Southern Denmark, Denmark
1992–1998 Group leader of the Protein & Peptide Group, European Molecular Biology Laboratory (EMBL), Heidelberg
1998–2007 Professor of Bioinformatics, Department of Biochemistry and Molecular Biology, University of Southern Denmark; Director of the Center for Experimental BioInformatics (CEBI)
2005– Director at the Max-Planck Institute of Biochemistry, Martinsried, Germany
2007– Additional appointment as director of the Department of Proteomics, The Novo Nordisk Foundation Center for Protein Research, Faculty of Heath Sciences, University of Copenhagen, Denmark


1991 Malcom Award by the journal Organic Mass Spectrometry
1996 Mattauch Herzog Prize in Mass Spectrometry
1997 Hewlett-Packard Prize for Strategic Research in Automation of Sample Preparation
1998 Edman Prize by the “Methods in Protein Structure Analysis” Society
1999 Bieman Medal for Outstanding Achievement in Mass Spectrometry (American Society for Mass Spectrometry)
1999 Named second most cited scientist in chemistry in the years 1994 to 1996 by the Institute of Scientific Information
1999 Elected visiting professor Harvard Medical School
1999 Elected to the European Molecular Biology Organization (EMBO)
2001 Bernhard and Matha Rasmussen’s Memorial award in Cancer Research
2001 Meyenburg Cancer Research Award
2001 Fesenius Prize for Analytical Chemistry by the German Chemical Society
2004 Honorary Doctorate University Utrecht, Netherlands
2004 Lundbeck Nordic Research Prize
2004 Novo-Nordisk Prize (shared with Prof. Peter Roepstorff)
2005 Anfinsen Award of the Protein Society
2006 Biochemical Analysis Prize by the German Society for Clinical Chemistry and Laboratory Medicine
2007 Honorary Professor at The Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen
2007 2nd most cited European Scientist for the last ten years according to ScienceWatch (ISI)
2008 HUPO Distinguished Achievement Award in Proteomic Sciences (Shared with Prof. Denis Hochstrasser)
2009 Honorary Degree awarded from University of Dundee
2010 Friedrich Wilhelm Joseph von Schelling Prize awarded by the Bavarian Academy of Sciences
2011 Fyodor Lynen Lecture Medal 2011 (German Society of Biochemistry and Molecular Biology)
2012 Leibniz Prize of the German Research Society
2012 Ernst Schering Prize
2012 Louis-Jeantet Foundation Prize for Medicine
2012 Körber European Science Award
2013 Elected member of Leopoldina German National Academy of Sciences
2013 Winner of m4 Award – Ministry of Economic Affairs supports Personalized Medicine
2015 Barry L. Karger Medal in Bioanalytical Chemistry
2015 Theodor Bücher Lecture and Medal
2015 Danish Order of Dannebrog Knights Cross
2017 Winner of Lennart Philipson Award

Current Editorial Board Memberships:

  • Carcinogenesis
  • Cell
  • Cell Systems
  • Clinical Mass Spectrometry
  • Molecular and Cellular Proteomics


Matthias Mann is currently involved in more than 6 external grants. Main sources: European Union, BMBF (The German Federal Ministry of Education and Research), Michael J Fox Foundation, Excellence Initiative of the Federal Republic of Germany and the German Research Foundation (DFG) as well as joint projects with various industrial concerns.


Dr. Mann has authored and co-authored more than 650 publications with over 160,000 citations according to ISI (h-factor more than 190), making him one of the most highly cited researchers worldwide

Ten most important publications (newest first)

  1. Aebersold R, Mann M. (2016) Mass-spectrometric exploration of proteome structure and function. Nature. 537(7620):347-55
  2. Geyer PE, Kulak NA, Pichler G, Holdt LM, Teupser D, Mann M. (2016) Plasma Proteome Profiling to Assess Human Health and Disease. Cell Syst.2(3):185-195
  3. MY Hein, NC Hubner, I Poser, J Cox, N Nagaraj, Y Toyoda, IA Gak, I Weisswange, J Mansfeld, F Buchholz, AA Hyman & M Mann. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell. 2015 Oct 22;163(3):712-23
  4. Vermeulen M, Eberl HC, Matarese F, Marks H, Denissov S, Butter F, Lee KK, Olsen JV, Hyman AA, Stunnenberg HG, Mann M. (2010) Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers. Cell. 142(6):967-80.
  5. Choudhary, C., Kumar, C., Gnad, F., Nielsen, M.L., Rehman, M., Walther, T.C., Olsen, J.V., and Mann, M. (2009). Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325, 834-840.
  6. de Godoy, L.M., Olsen, J.V., Cox, J., Nielsen, M.L., Hubner, N.C., Frohlich, F., Walther, T.C., and Mann, M. (2008). Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast. Nature 455, 1251-1254.
  7. Olsen, J.V., Blagoev, B., Gnad, F., Macek, B., Kumar, C., Mortensen, P., and Mann, M. (2006). Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks. Cell 127, 635-648.
  8. Ong, S.E., Blagoev, B., Kratchmarova, I., Kristensen, D.B., Steen, H., Pandey, A., and Mann, M. (2002). Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics. Mol Cell Proteomics 1, 376-386.
  9. Mann, M., and Wilm, M.S. (1994). Error Tolerant Identification of Peptides in Sequence Databases by Peptide Sequence Tags. Analytical Chemistry 66, 4390-4399.
  10. Wilm, M., Shevchenko, A., Houthaeve, T., Breit, S., Schweigerer, L., Fotsis, T., and Mann, M. (1996). Femtomole Sequencing of Proteins from Polyacrylamide Gels by Nano Electrospray Mass Spectrometry. Nature 379, 466 - 469.
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