Genome Biology 2007, 8:R250doi:10.1186/gb-2007-8-11-r250 Published: 26 November 2007

Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation

Florian Gnad, Shubin Ren, Juergen Cox, Jesper V. Olsen, Boris Macek, Mario Oroshi and Matthias Mann

Proteomics and Signal Transduction, Max-Planck-Institute for Biochemistry, Munich 82152

 

PHOSIDA http://www.phosida.com, a phosphorylation site database, integrates thousands of high-confidence in-vivo phosphosites identified by mass spectrometry-based proteomics in various species. For each phosphosite, PHOSIDA lists matching kinase motifs, predicted secondary structures, conservation patterns, and its dynamic regulation upon stimulus. Using support vector machines, PHOSIDA also predicts phosphosites.

 

http://genomebiology.com/2007/8/11/R250

 

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