Contact

Dr. Zuzana Storchova
Group Leader
Phone:+49 89 8578 - 3145

MPI of Biochemistry, Am Klopferspitz 18, 82152 Martinsried

www.biochem.mpg.de/storchova

Maintenance of Genome Stability

Research Group "Maintenance of Genome Stability"

NEWS

Our research group is moving to the University of Kaiserslautern. The laboratory in Munich will be closed by end of 2016.

 

We recently published following articles:

Kuznetsova AY, Seget K, Moeller GK, de Pagter MS, de Roos JADM, Dürrbaum M, Kuffer C, Müller S, Zaman GJR, Kloosterman WP, Storchová Z (2015) Whole genome doubling promotes chromosomal instability, tolerance of mitotic errors and multidrug resistance, Cell Cycle 14: 2810-20.

 

Donnelly N, Passerini V, Dürrbaum M, Stingele S, Storchová Z (2014) HSF1 deficiency and impaired HSP90-dependent protein folding are hallmarks of aneuploid human cells, EMBO Journal 33:2374-87.

 

Peplowska K, Wallek AU, Storchová Z (2014) Sgo1 Regulates both Condensin and Ipl1/Aurora B to Promote Chromosome Biorientation, PLoS Genet. 10: e1004411.

 

Dürrbaum M, Kuznetsova AY, Passerini V, Stingele S, Stoehr G, Storchová Z (2014) Unique features of the transcriptional response to model aneuploidy in human cells. BMC Genomics 2014, 15:139 - 52.

 

and reviews:

Donnelly N, Storchová Z (2015) Causes and consequences of protein folding stress in aneuploid cells, Cell Cycle, 14:4, 495-501.

 

Donnelly N, Storchová Z (2015) Aneuploidy and proteotoxic stress in cancer, Molecular & Cellular Oncology, 2: e976491

 

Dürrbaum M, Storchová Z (2015) Effects of aneuploidy on gene expression: implications for cancer, FEBS J. doi: 10.1111/febs.13591.

 

 

 

Current funding:

 

Max Planck Society

 

Deutsche Forschungsgemeinschaft (Project "Maintenance of proteostasis in human aneuploid cell lines")

 

Center of Integrated Protein Science - Cluster of Excellence

 

International Training Network – Marie Curie Action PloidyNet

 
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