The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production.Virology. 2014 Aug;462-463:34-41. Eberle C.A., Zayas M., Stukalov A., Pichlmair A., Alvisi G., Müller A.C., Bennett K.L., Bartenschlager R. and Superti-Furga G.

Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH.J Virol. 2014 Mar;88(6):3464-73. Kainulainen M., Habjan M., Hubel P., Busch L., Lau S., Colinge J., Superti-Furga G., Pichlmair A. and Weber F.

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection.Nat Med. 2014 Jan;20(1):47-53. Liehl P., Zuzarte-Luís V., Chan J., Zillinger T., Baptista F., Carapau D., Konert M., Hanson K.K., Carret C., Lassnig C., Müller M., Kalinke U., Saeed M., Chora A.F., Golenbock D.T., Strobl B., Prudêncio M., Coelho L.P., Kappe S.H., Superti-Furga G., Pichlmair A., Vigário A.M., Rice C.M., Fitzgerald K.A., Barchet W. and Mota M.M.

Viperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activity. Cell Microbiol. 2013 Nov 19. doi: 10.1111. Upadhyay A.S., Vonderstein K., Pichlmair A., Stehling O., Bennett K.L., Dobler G., Guo J.T., Superti-Furga G., Lill R., Overby A.K., Weber F.


Sequestration by IFIT1 impairs translation of 2'O-unmethylated capped RNA. PLoS Pathog. 2013 Oct;9(10):e1003663. Habjan M., Hubel P., Lacerda L., Benda C., Holze C., Eberl C.H., Mann A., Kindler E., Gil-Cruz C., Ziebuhr J., Thiel V., Pichlmair A

Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins. Nature. 2013 Feb 7;494(7435).60-4. Abbas, YM., Pichlmair, A., Górna, MW., Superti-Furga, G., Nagar, B


Viral immune modulators perturb the human molecular network by common and unique strategies. Nature. 2012 Jul 26;487(7408):486-90. Pichlmair, A., Kandasamy, K., Alvisi, G., Mulhern, O., Sacco, R., Habjan, M., Binder, M., Stefanovic, A., Eberle, C.A., Goncalves, A., Bürckstümmer, T., Müller, A., Fauster, A., Holze, C., Lindsten, K., Goodbourn, S., Kochs, G., Weber, F., Bartenschlager, R., Bowie, A.G., Bennett, K.L., Colinge, J. and Superti-Furga. G


IFIT1 is an antiviral protein that recognizes 5’-triphosphate RNA. Nat Immunol 2011 Jun 5;12(7):624-30. Pichlmair, A., Lassnig. C., Eberle C.A., Górna M.W., Baumann C.L., Burkard T.R., Bürckstümmer T., Stefanovic A., Krieger S., Bennett K.L., Rülicke T., Weber F., Colinge J., Müller M., Superti-Furga G


CD14 is a coreceptor of Toll-like receptors 7 and 9.; J Exp Med. 2010 Nov 22;207(12):2689-701. Baumann, C.L., Aspalter, I.M., Sharif, O., Pichlmair. A., Blüml, S., Grebien, F., Bruckner, M., Pasierbek, P., Aumayr, K., Planyavsky, M., Bennett, K.L., Colinge, J., Knapp, S., Superti-Furga, G

Virus-Like Particles Expressing the Nucleocapsid Gene as an Efficient Vaccine Against Rift Valley Fever Virus. Vector-Borne and Zoonotic Diseases, 2010 Oct;10(7):701-3. Pichlmair, A., Habjan, M., Unger, H., Weber, F

Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity.; Cell Host Microbe. 2010 May 20;7(5):354-61. Schulz, O., Pichlmair, A., Rehwinkel, J., Rogers, NC., Scheuner, D., Kato, H., Takeuchi, O., Akira, S., Kaufman, RJ., Reis e Sousa, C

RIG-I detects viral genomic RNA during negative-strand RNA virus infection. Cell. 2010 Feb 5;140(3):397-408. Rehwinkel, J., Tan, CP., Goubau, D., Schulz, O., Pichlmair, A., Bier, K., Robb, N., Vreede, F., Barclay, W., Fodor, E., Reis e Sousa, C


Activation of MDA5 requires higher-order RNA structures generated during virus infection.; J Virol. 2009 Oct;83(20):10761-9. Pichlmair, A., Schulz, O., Tan, CP., Rehwinkel, J., Kato, H., Takeuchi, O., Akira, S., Way, M., Schiavo, G., Reis e Sousa, C

NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase; J Virol. 2009 May; 83(9):4365-75. Habjan, M.*, Pichlmair, A.*, Elliott, RM., Overby, AK., Glatter, T., Gstaiger, M., Superti-Furga, G., Unger, H., Weber, F

*contributed equally


Processing of genome 5' termini as a strategy of negative-strand RNA viruses to avoid RIG-I-dependent interferon induction; PLoS One. 2008 Apr 30; 3(4):e2032. Habjan, M., Andersson, I., Klingström, J., Schümann, M., Martin, A., Zimmermann, P., Wagner, V., Pichlmair, A., Schneider, U., Mühlberger, E., Mirazimi, A., Weber, F


Innate recognition of viruses; Immunity, 2007, Sep 21;27(3): 370-383. Pichlmair, A. and Reis e Sousa, C

Tubulovesicular Structures within Vesicular Stomatitis Virus G Protein-Pseudotyped Lentiviral Vector Preparations Carry DNA and Stimulate Antiviral Responses via Toll-Like Receptor 9; J Virol., 2007, Jan; 81(2): 539-47. Pichlmair, A., Diebold, S.S., Gschmeissner, S., Takeuchi, Y., Ikeda, Y., Collins, M.K. and Reis e Sousa, C


RIG-I-mediated antiviral responses to single stranded RNA bearing 5’ phosphates; Science, 2006, Nov; 314: 997-1001. Pichlmair, A., Schulz, O., Tan, C.P., Näslund, T.I., Liljeström, P., Weber, F. and Reis e Sousa, C


Inhibition of interferon-beta induction by SARS coronavirus suggests a two-step model for activation of interferon regulatory factor 3; J Virol., 2005, Feb; 79(4): 2079-86. Spiegel, M., Pichlmair, A., Martínez-Sobrido, L., Cros, J., García-Sastre, A., Haller, O. and Weber, F


Thogoto Virus lacking interferon – antagonistic factor ML is strongly attenuated in Mx1-positive but not Mx1-negative mice; J Virol., 2004, Oct; 78(20): 11422-4. Pichlmair, A., Buse, J., Jennings, S., Haller, O., Kochs, G. and Staeheli, P

The first answer to viral infections: Type I Interferons [german]; BMTW, 2004, Jul-Aug; 117: 252-265. Pichlmair, A., Pollak, M., Bergthaler, A

The antiviral effect of interferon-beta against SARS-Coronavirus is not mediated by MxA protein; J Clin Virol., 2004, Jul; 30(3): 211-3. Spiegel, M., Pichlmair, A., Muehlberger, E., Haller, O. and Weber, F


Retrospective and prospective screening for West Nile virus infections in susceptible species in Austria; Epidemiol Infect. 2003 Oct; 131(2): 1023-7. Weissenbock, H., Hubálek, Z., Halouzka, J., Pichlmair, A., Maderner, A., Fragner, K., Kolodziejek, J., Loupal, G., Kölbl, S. and Nowotny, N

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