MPI für Biochemie  

Innate Immunity
Andreas Pichlmair

 

Viral RNA in Cells
Viral RNA (green) in picornavirus infected cell

Co-occurrence of microbes and host organisms takes place since millions of years and resulted in intimate interactions between both players. The majority of such interactions do not cause disease and microbes are controlled by the host. Encounter of pathogenic microorganisms, however, can lead to disease. We are interested in understanding interactions between pathogenic viruses and their hosts on molecular and functional level, focusing on RNA-protein and protein-protein interactions.