Curriculum Vitae
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Dr. Boris Pfander |
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Address: |
Max-Planck Institute of Biochemistry
Am Klopfersptz 18 82152 Martinsried, Germany |
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Phone: |
+49-89-8578-3050 |
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Fax: |
+49-89-8578-3022 |
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Email: |
bpfander[at]biochem.mpg.de |
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Internet: |
http://www.biochem.mpg.de/pfander |
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Education: |
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2001 - 2005 |
Ludwig-Maximilians University Munich, Germany:
PhD – Biology |
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PhD Thesis on “Regulation of genome stability by SUMO- and ubiquitin-modification of PCNA“ (Supervisor: Stefan Jentsch) |
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1995 - 2000 |
University of Hannover & Hannover Medical School, Hannover, Germany:
Diploma – Biochemistry |
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Diploma Thesis on “Characterization of NGF-induced phosphorylation of endocytotic proteins in PC12-cells“ (Supervisor: Rudolf Bauerfeind) |
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Research Experience: |
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Since 2010 |
Independent Junior Group Leader (Otto-Hahn-Nachwuchsgruppe)
at the Max-Planck Institute of Biochemistry |
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2006 - 2010 |
Postdoctoral fellow with John Diffley at the London Research Institute,
CRUK, South Mimms, UK |
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2005 - 2006 |
Postdoctoral fellow with Stefan Jentsch at the Max Planck Institute of
Biochemistry, Martinsried, Germany |
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2001 - 2005 |
PhD work with Stefan Jentsch at the Max Planck Institute of
Biochemistry, Martinsried, Germany |
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2000 |
Undergraduate work with Rudolf Bauerfeind at the Hannover Medical
School, Hannover, Germany |
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Fellowships and Awards: |
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2007- 2010 |
Human Frontier Science Program Long Term Fellowship |
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2007 |
EMBO Long Term Fellowship |
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2006 |
Otto-Hahn Program (Max-Planck Society, Germany) |
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2006 |
Otto-Hahn Medal (Max-Planck Society, Germany) |
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2006 |
MPIB Junior Research Award (Max-Planck Institute of Biochemistry, Martinsried, Germany) |
Peer-reviewed Publications:
Pfander, B., and Diffley, J.F.X. (2011) Dpb11 coordinates Mec1 kinase activationwith cell cycle-regulated Rad9 recruitment. EMBO J. doi:10.1038/emboj.2011.345
Parnas, O., Zipin-Roitman, A., Pfander, B., Liefshitz, B., Mazor Y., Ben-Aroya, S., Jentsch, S., and Kupiec, M. (2010). Elg1, an alternative subunit of the RF-C clamploader, preferentially interacts with SUMOylated PCNA. EMBO J.29(15):2611-22
Sacher, M., Pfander, B., Hoege, C., Jentsch, S. (2006). Control of Rad52 recombination activity by double-strand break-induced SUMO modification. Nature Cell Biology. 8, 1284-1290.
Moldovan, G.-L., Pfander, B., Jentsch, S. (2006). PCNA controls establishment of sister chromatid cohesion during S-phase. Molecular Cell. 23, 723-732.
Döring, M., Loos, A., Schrader, N., Pfander, B., Bauerfeind, R. (2006). Nerve growth factor-induced phosphorylation of amphiphysin-1 by casein kinase 2 regulates clathrin-amphiphysin interactions. Journal of Neurochemistry. 98, 2013-2023
Pfander, B., Moldovan, G.-L., Sacher, M., Hoege, C., Jentsch, S. (2005). SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase. Nature 436, 428-433.
Hoege, C., Pfander, B., Moldovan, G.-L., Pyrowolakis, G., Jentsch, S. (2002). RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419, 135-141.
Review Articles and Book Chapters:
Moldovan, G.-L., Pfander, B., Jentsch, S. (2007). PCNA, the maestro of the replication fork. Cell.129, 665-679.
Sacher, M.*, Pfander, B.*, Jentsch, S. (2005). Identification of SUMO-protein conjugates. Methods in Enzymology 399, 392-404.
* equal contribution