MPI für Biochemie  

DNA Replication & Genome Integrity
Boris Pfander

Curriculum Vitae

 

 

Dr. Boris Pfander

 

Address:

Max-Planck Institute of Biochemistry

Am Klopfersptz 18

82152 Martinsried, Germany

Phone:

+49-89-8578-3050

Fax:

+49-89-8578-3022

Email:

bpfander[at]biochem.mpg.de

Internet:

http://www.biochem.mpg.de/pfander

 

 

Education:

 

2001 - 2005

Ludwig-Maximilians University Munich, Germany:

PhD – Biology

 

PhD Thesis on “Regulation of genome stability by SUMO- and ubiquitin-modification of PCNA“ (Supervisor: Stefan Jentsch)

1995 - 2000

University of Hannover & Hannover Medical School, Hannover, Germany:

Diploma – Biochemistry

 

Diploma Thesis on “Characterization of NGF-induced phosphorylation of endocytotic proteins in PC12-cells“ (Supervisor: Rudolf Bauerfeind)

 

 

Research Experience:

 

Since 2010

Independent Junior Group Leader (Otto-Hahn-Nachwuchsgruppe)

at the Max-Planck Institute of Biochemistry

2006 - 2010

Postdoctoral fellow with John Diffley at the London Research Institute,

CRUK, South Mimms, UK

2005 - 2006

Postdoctoral fellow with Stefan Jentsch at the Max Planck Institute of

Biochemistry, Martinsried, Germany

2001 - 2005

PhD work with Stefan Jentsch at the Max Planck Institute of

Biochemistry, Martinsried, Germany

2000

Undergraduate work with Rudolf Bauerfeind at the Hannover Medical

School, Hannover, Germany

 

 

Fellowships and Awards:

 

2007- 2010

Human Frontier Science Program Long Term Fellowship

2007

EMBO Long Term Fellowship

2006

Otto-Hahn Program (Max-Planck Society, Germany)

2006

Otto-Hahn Medal (Max-Planck Society, Germany)

2006

MPIB Junior Research Award (Max-Planck Institute of Biochemistry, Martinsried, Germany)
 

 

Peer-reviewed Publications:

 

Pfander, B., and Diffley, J.F.X. (2011) Dpb11 coordinates Mec1 kinase activationwith cell cycle-regulated Rad9 recruitment. EMBO J. doi:10.1038/emboj.2011.345

 

Parnas, O., Zipin-Roitman, A., Pfander, B., Liefshitz, B., Mazor Y., Ben-Aroya, S., Jentsch, S., and Kupiec, M. (2010). Elg1, an alternative subunit of the RF-C clamploader, preferentially interacts with SUMOylated PCNA. EMBO J.29(15):2611-22

 

Sacher, M., Pfander, B., Hoege, C., Jentsch, S. (2006). Control of Rad52 recombination activity by double-strand break-induced SUMO modification. Nature Cell Biology. 8, 1284-1290.

 

Moldovan, G.-L., Pfander, B., Jentsch, S. (2006). PCNA controls establishment of sister chromatid cohesion during S-phase. Molecular Cell. 23, 723-732.

 

Döring, M., Loos, A., Schrader, N., Pfander, B., Bauerfeind, R. (2006). Nerve growth factor-induced phosphorylation of amphiphysin-1 by casein kinase 2 regulates clathrin-amphiphysin interactions. Journal of Neurochemistry. 98, 2013-2023

 

Pfander, B., Moldovan, G.-L., Sacher, M., Hoege, C., Jentsch, S. (2005). SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase. Nature 436, 428-433.

 

Hoege, C., Pfander, B., Moldovan, G.-L., Pyrowolakis, G., Jentsch, S. (2002). RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419, 135-141.

 

 

Review Articles and Book Chapters:

 

Moldovan, G.-L., Pfander, B., Jentsch, S. (2007). PCNA, the maestro of the replication fork. Cell.129, 665-679.

 

Sacher, M.*, Pfander, B.*, Jentsch, S. (2005). Identification of SUMO-protein conjugates. Methods in Enzymology 399, 392-404.

* equal contribution