Contact

profile_image
Dr. Julia von Blume
Group Leader
Phone:+49 89 8578-2466

www.biochem.mpg.de/blume

Molecular Basis of Protein Trafficking

Publications

Original Publications

 

  • Crevenna, A H, Blank, B, Maiser, A., Emin, D, Prescher, J, Beck, G, Kienzle, C, Bartnik, K, Habermann, B, Pakdel, M, Leonhardt, H, Lamb, D C, von Blume, J. Secretory cargo sorting by Ca2+-dependent Cab45 oligomerization at the trans-Golgi Network. 2016. 3

  • Kienzle C, Basnet N, Crevenna AH, Beck G, Habermann B, Mizuno M, von Blume J. Cofilin recruits F-actin to SPCA1 and promotes Ca2+-mediated secretory cargo sorting. 2014. J Cell Biol. 206(5): 635-54. (Highlighted in biobytes, September 152014).


  • Boztug K, Järvinen PM, Salzer E, Racek T, Mönch S, Garncarz W, Gertz EM, Schäffer AA, Antonopoulos A, Haslam SM, Schieck L, Puchałka J, Diestelhorst J, Appaswamy G, Lescoeur B, Giambruno R, Bigenzahn JW, Elling U, Pfeifer D, Conde CD, Albert MH, Welte K, Brandes G, Sherkat R, van der Werff Ten Bosch J, Rezaei N, Etzioni A, Bellanné-Chantelot C, Superti-Furga G, Penninger JM, Bennett KL, von Blume J, Dell A, Donadieu J, Klein C. JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia. 2014. Nat Genet. 46 (9): 1021-1027.


  • von Blume J#, Alleaume AM, Kienzle C, Carreras-Sureda M, Valverde M, and Malhotra V#. Cab45 is required for Ca2+-dependent secretory cargo sorting at the trans-Golgi network. 2012. J Cell Biol. 199 (7). (corresponding authors#). (Highlighted in J Cell Biol “Secretory proteins hail a cab at the TGN”)


  • Curwin AJ, von Blume J, Malhotra V. Cofilin mediated sorting and export of specific cargo from the Golgi apparatus in yeast. 2012. Mol Biol Cell. 23 (12): 2327-38.

  • von Blume J, Alleaume AM, Cantero-Recasens G, Curwin A, Carreras-Sureda A, Zimmermann T, van Galen J, Wakana Y, Valverde MA, Malhotra V. ADF/cofilin regulates secretory cargo sorting at the TGN via the Ca2+ ATPase SPCA1. 2011. Dev Cell. 20 (5): 652-62.

  • Pusapati GV, Krndija D, Armacki M, von Wichert G, von Blume J, Malhotra V, Adler G, Seufferlein T. Role of the Second Cysteine-rich Domain and Pro275 in PKD2 Interaction with ARF1, TGN Recruitment and Protein Transport. 2010. Mol Biol Cell. (21): 1011-1022.

  • von Blume J, Duran JM, Forlanelli E, Alleaume AM, Egorov M, Polishchuk R, Molina H, Malhhotra V. Actin remodelling by ADF/cofilin is required for cargo sorting at the trans Golgi network. 2009. J Cell Biol. 187 7: 1055-69.

  • von Wichert G, Edenfeld T, von Blume J, Krisp H, Krindja D, Schmid H, Oswald F, Lother U, Walther P, Adler G, Seufferlein T. Protein kinase D2 regulates chromogranin A secretion in human BON neuroendrcrine tumour cells. 2008. Cell Signal. 5: 925-34.

  • von Blume J, Knippschild U, Dequiedt F, Georgios Giamas G, Beck A, Auer A, Van Lint J, Adler G, Seufferlein T. Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2. 2007. EMBO J. 22: 4619-4633.

  • Dequiedt F, Martin M+, von Blume J+, Vertommen D, Lecomte E, Mari N, Heinen M-F, Bachmann M, Twizere JC, Huang MC, Rider MH, Piwnica-Worms H, Seufferlein T, Kettmann R. New Role for hPar-1 Kinases EMK and C-TAK1 in Regulating Localization and Activity of Class IIa Histone Deacetylases. 2006. Mol Cell Biol. 26: 7086-7102. (+ authors have contributed equally).

  • Auer A+, von Blume J+, Sturany S, von Wichert G, Van Lint J, Vanderheede J, Adler G. Role of the regulatory domain of Protein Kinase D2 in phorbol ester binding, catalytic activity and nucleo-cytoplasmic shuttling. 2005. Mol Biol Cell. 16: 4375-4385. (+authors have contributed equally).



Reviews and perspectives


  • Kienzle C, von Blume J. Secretory cargo sorting at the trans-Golgi network. 2014. Trends Cell Biol. 24(10): 584-593.
    (Editorially selected as best review in the year 2014).

  • von Blume J, Sedwick C. Julia von Blume: sorting through the trans-Golgi.
    J Cell Biol. 2015 Jan 5;208(1):4-5. PMID: 25559180

  • Antonny B, Audhya J, l Bagnat M, von Blume J, Briggs JA, Giraudo C, Kaeser PS, Miller E, Reinisch K, Sbalzarini IF, Schuldiner M, Shen J, Takamori S, Verstreken P, Walther T. Directing traffic into the future. 2013. Dev Cell. 27 480-4.
 
loading content