Stable isotope labeling by amino acids in cell culture for quantitative proteomics.
Cell, Vol 130, 395-398, 10 August 2007
Jürgen Cox and Matthias Mann,*
Mass spectrometry (MS)-based proteomics has become a formidable tool for the investigation of posttranslational modifications to proteins, protein interactions, and organelles. Is it now ready to tackle comprehensive protein expression analysis?