Selected Publications:

1.  Saschenbrecker, S., Bracher, A., Vasudeva Rao, K., Vasudeva Rao, B., Hartl, F.U. and Hayer-Hartl, M.(2007). Structure and Function of RbcX, a specific assembly chaperone for hexadecameric Rubisco. Cell 129, 1189-1200.

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2.  Tang, Y-C, Chang, H-C., Hayer-Hartl, M., and Hartl, F.U. (2007). SnapShot: Molecular Chaperones, Part II. Cell 128, 412-412.e1.

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3.  Chang, H-C., Tang, Y-C., Hayer-Hartl, M., and Hartl, F.U. (2006). SnapShot: Molecular Chaperones, Part I. Cell 128, 212.e1-412.e2.

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4.  Hayer-Hartl, M. and Minton, A.P. (2006). A simple semi-empirical model for the effect of molecular confinement upon the rate of protein folding. Biochemistry 45, 13356-13360.

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5.  Tang, Y-C., Chang, H-C., Roeben, A., Wischnewski, D., Wischnewksi, N., Kerner, M.J., Hartl, F.U. and Hayer-Hartl, M. (2006). Structural features of the GroEL-GroES nano-cage required for rapid folding of encapsulated protein. Cell 125, 903-914.

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6.  Kerner, M.J., Naylor, D.J., Yasushi, I., Tobias, M., Chang, H-C., Stines, A.P., Georgopoulos, C., Frishman, D., Hayer-Hartl, M., Mann, M. and Hartl, F.U. (2005) Proteome-wide analysis of chaperonin-dependent protein folding in Escherichia coli. Cell 122 (2), 209-220.

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7.  Figueiredo, L., KlunkerD., Ang, D, Naylor, D.J., Kerner, M.J., Georgopoulos, C., Hartl, F.U. and Hayer-Hartl, M. (2004) Functional characterization of an archaeal GroEL/GroES chaperonin system: Significance of substrate encapsulation.  J. Biol. Chem. 279 (2), 1090-1099.

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8.  KlunkerD., Bernd, H., Hirtreiter, A., Figueiredo, L., Naylor, D.J., Pfeifer, G., Müller, V., Deppenmeier, U., Gottschalk, G., Hartl, F.U. and Hayer-Hartl, M. (2003) Coexistence of group I and group II chaperonins in the archaeon Methanosarcina mazei.  J. Biol. Chem. 278 (35), 33256-33267.

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9.  Hartl, F.U. and Hayer-Hartl, M.(2002) Molecular Chaperones in the Cytosol: From Nascent Chain to Folded Protein.  Science 295, 1852-1858.

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10.  Brinker, A., Pfeifer, G., Kerner, M.J., Naylor, D.J., Hartl, F.U. and Hayer-Hartl, M.(2001) Dual function of protein confinement in chaperonin-assisted protein folding.  Cell 107, 223-233.

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11.  Hayer-Hartl, M.K. (2000) Assay of malate dehydrogenase - a substrate for the E. coli chaperonins GroEL and GroES.  Book chapter in "Chaperonin Protocols" Ed. Schneider, C.  Humana Press Inc. 127-132.

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12.  Weber, F. and Hayer-Hartl, M.K. (2000) Refolding of bovine mitochondrial rhodanese by chaperonins GroEL and GroES.  Book chapter in "Chaperonin Protocols" Ed. Schneider, C.  Humana Press Inc. 117-126.

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13.  Weber, F. and Hayer-Hartl, M.K. (2000) Prevention of rhodanese aggregation by the chaperonin GroEL.  Book chapter in "Chaperonin Protocols" Ed. Schneider, C.  Humana Press Inc. 111-115.

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14.  Hayer-Hartl, M.K., Ewalt, K.L. and Hartl, F.U. (1999) On the role of symmetrical and asymmetrical chaperonin complexes in assisted protein folding. Biol. Chem., 380, 531-540.

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15.  Weber, F., Keppel, F., Georgopoulos, C., Hayer-Hartl, M.K. and Hartl, F.U. (1998) The oligomeric cage of GroEL-GroES is required for biologically significant chaperonin function in protein folding. Nat. Struct. Biol., 5(11), 977-985.  Erratum: Nat. Struct. Biol., 6(2), 200-200.

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16.  Harrison, C.J., Hayer-Hartl, M.K., Di Liberto, M., Hartl, F.U. and Kuriyan, J. (1997) Crystal structure of the nucleotide exchange factor GrpE bound to the ATPase domain of the molecular chaperone DnaK. Science, 276, 431-435.

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17. Hayer-Hartl, M.K., Weber, F. and Hartl, F.U. (1996) Mechanism of chaperonin action: GroES-binding and release can drive GroEL-mediated folding in the absence of ATP-hydrolysis. EMBO J., 15(22), 6111-6121.

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18. Hayer-Hartl, M.K., Martin, J. and Hartl, F.U. (1995) Asymmetrical interaction of GroEL and GroES in the ATPase cycle of assisted protein folding. Science, 269, 836-841.

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19. Engel, A., Hayer-Hartl, M.K., Goldie,K.N., Pfeifer, G., Hegerl, R., Muller, S., Rasera da Silva, A., Baumeister, W. and Hartl, F.U. (1995) Functional significance of symmetrical versus asymmetrical GroEL-GroES chaperonin complexes. Science, 269, 832-836

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20. Hayer-Hartl, M.K., Ewbank, J., Creighton, T. and Hartl, F.U. (1994) Conformational specificity of the chaperonin GroEL for the compact intermediates of a-lactalbumin.  EMBO J., 13(13), 3192-3202.

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