MPI für Biochemie  

Emeritus Group Membrane and Neurophysics
Peter Fromherz

 

Technology aspects of a CMOS Neuro-Sensor: Back End Process and Packaging

Franz Hofmann, Björn Eversmann, Martin Jenkner, Alexander Frey, Matthias Merz, Tamara Birkenmaier, Peter Fromherz, Matthias Schreiter, Reinhard Gabl, Kurt Plehnert, Michael Steinhauser, Gerald Eckstein, Roland Thewes
ESSDERC

Abstract

A CMOS-compatible process is presented which allows to realize sensor arrays for non-invasive, extracellular, high density, long term recording of neural activity. A high-permittivity bio-compatible dielectric is used to capacitivly couple nerve cell-induced biological signals to the CMOS circuitry-based electronic world. The transducer consists of a multi layer of TiO2 and ZrO2 and is fabricated in the backend of a 0.5 µm standard CMOS technology. Living cells are cultured within a specific package on top of the sensor chip. First measurements reveal proper operation of the chip.