Microelectronics meets Molecular and Neurobiology
Peter Fromherz
Technical Digest IEDM (International Electronic Devices Meeting) 2001, 16/1
Abstract
The electrical interfacing of nerve cells and semiconductor microstructures is considered.
The coupling of the electron conducting silicon with ion conducting neurons relies on a
close contact of the chip and the cell membrane with its ion channels. Excitation of neuronal
activity is achieved by capacitive interaction with the channels and recording by the
response of transistors to open channels. Integrated neuroelectronic systems are obtained by
outgrowth of a neuronal net on silicon and by two-way interfacing of the neuronal and
electronic components.