Structure Gallery

Mpp6-bound Yeast Exosome
5okz

Falk S. et al. Cell Rep. 2017

pdb entry:

5okz

Yeast Sen1 helicase
5mzn

Leonaitė B, Han Z et al. EMBO J. 2017

pdb entry:

5mzn

Smg8-Smg9 complex
5nkk

Li L et al. RNA. 2017

pdb entries:

5nkk (GDP bound)

5nkm (apo)

Yeast Ski2-3-8 complex bound to 80S ribosome
5jea

Schmidt C et al. Science. 2016

pdb entry:

5mc6

RBM7-ZCCHC8 core of the NEXT complex
5lxr

Falk S, Finogenova K et al. Nat Commun. 2016

pdb entries:

5lxr (with Samarium)

5lxy (apo)

11-subunit Yeast Cytoplasmic RNA-Exosome including Ski7
5jea

Kowalinski E et al. Mol Cell. 2016

pdb entry:

5jea

C. elegans Gld2-Rnp8 complex
5jnb

Nakel K et al. RNA. 2016

pdb entry:

5jnb

Drosophila MLE in complex with RNA in the transition state
5aor

Prabu JR, Müller M, et al. Mol Cell. 2015

pdb entry:

5aor

Human DDX6 in complex with CNOT1 and 4E-T
5anr

Ozgur S et al. Cell Rep. 2015

pdb entry:

5anr

12-subunit yeast nuclear exosome bound to single-stranded RNA substrates
4zrl

Makino DL, Schuch B et al. Nature. 2015

pdb entry:

5c0w

12-subunit yeast nuclear exosome bound to structured RNA
4zrl

Makino DL, Schuch B et al. Nature. 2015

pdb entry:

5c0x

yeast Rrp6 catalytic domain bound to poly(U) RNA
4zrl

Makino DL, Schuch B et al. Nature. 2015

pdb entry:

5c0y

C. elegans Gld2-Gld3 complex
4zrl

Nakel K et al. PNAS. 2015

pdb entry:

4zrl


Ski7 loaded with GTP or GDP-Pi
4zke

Kowalinski E et al. Structure. 2015

pdb entries:

4zkd (GDP-Pi)

4zke (GTP)


Not4 ring domain in complex Ubc4
5aie

Bhaskar V et al. Structure. 2015

pdb entry:

5aie


Not1 C-terminal domain in complex with Not4
5ajd

Bhaskar V et al. Structure. 2015

pdb entry:

5ajd


Rrp6-Rrp47-Mtr4 interaction
4q8j

Schuch B et al. EMBO J. 2014

pdb entries:

4wfd (Rrp6-Rrp47-Mtr4)

4wfc (Rrp6-Rrp47)


Pyrococcus furiosus Cmr6
4q8j

Benda C et al. Mol Cell. 2014

pdb entry:

4w8v


Pyrococcus furiosus Cmr4
4q8j

Benda C et al. Mol Cell. 2014

pdb entry:

4w8w


Pyrococcus furiosus Cmr2
4q8j

Benda C et al. Mol Cell. 2014

pdb entry:

4w8y


Pyrococcus furiosus Cmr1
4q8j

Benda C et al. Mol Cell. 2014

pdb entries:

4w8z (Apo)

4w8x (with GDP)


Minimal yeast TRAMP complex
4ct7 width=

Falk S, Weir JR et al. Mol Cell. 2014

pdb entry:

4u4c


Thermofilum pendens Csc2
4ct7 width=

Hrle A et al. RNA Biol. 2014

pdb entry:

4txd


TPR domain of Human SMG6
4ct7 width=

Chakrabarti S et al. Nucleic Acids Res. 2014

pdb entry:

4um2


Yeast Pan2-Pan3 core complex
4q8j

Schäfer IB et al. Nat Struct Mol Biol. 2014

pdb entries:

4q8j(Pan2-Pan3 core)

4q8g(Pan2 pseudoubiquitin-hydrolase domain)

4q8h(Pan2 pseudoubiquitin-hydrolase-RNase module)


Human CNOT1 C9BD domain in complex with CNOT9 and bound tryptophan
4ct7 width=

Mathys H, Basquin J et al. Mol Cell. 2014

pdb entries:

4ct7(with tryptophan)

4ct6(without tryptophan)

4cv5(yeast proteins)


Human CNOT1 MIF4G domain in complex with DDX6
4ct7 width=

Mathys H, Basquin J et al. Mol Cell. 2014

pdb entry:

4ct4


Human DDX6
4ct7 width=

Mathys H, Basquin J et al. Mol Cell. 2014

pdb entry:

4ct5


eIF4AIII-CWC22 complex
4c9b

Buchwald G et al. PNAS. 2013

pdb entry:

4c9b


Methanopyrus kandleri Csm3
4n0l

Hrle A, Su AA et al. RNA Biol. 2013

pdb entry:

4n0l


Lsm1-7-Pat1 Complex
4c8q

Sharif H, Conti E. Cell Reports. 2013

pdb entry:

4c8q


Lsm1-7 Complex
4c92

Sharif H, Conti E. Cell Reports. 2013

pdb entry:

4c92


Not module of the yeast CCR4-Not complex
4by6

Bhaskar V et al. Nat Struct Mol Biol. 2013

pdb entry:

4by6


Yeast SKI complex
4buj

Halbach F et al. Cell. 2013

pdb entry:

4buj


Dhh1 in complex with Pat1 or Edc3
4brw

Sharif H et al. Nucleic Acids Res. 2013

pdb entries:

4bru (Edc3)

4brw (Pat1)


SLIP1 in complex with SLBP or Dbp5
4jhk

von Moeller H et al. Nucleic Acids Res. 2013

pdb entries:

4jhj (Dbp5)

4jhk (SLBP)


11-subunit yeast exosome bound to RNA
4ifd

Makino DL et al. Nature. 2013

pdb entry:

4ifd


Archaeal exosome in pre-catalytic state
4ba2

Lorentzen E et al. Archaea. 2012

pdb entries:

4ba1 (with inorganic phosphate)

4ba2 (with RNA and inorganic phosphate)


Nuclease module of the yeast CCR4-Not complex
4b8c

Basquin J, Roudko VV et al. Mol Cell. 2012

pdb entries:

4b89 (MIF4G domain of NotI)

4b8a (MIF4G domain of NotI with Caf1)

4b8c (Nuclease module of the CCR4-Not complex)


Not1 N-terminal domain
4b8b

Basquin J, Roudko VV et al. Mol Cell. 2012

pdb entries:

4b8b


Ska core complex
4aj5

Jeyaprakash AA et al. Mol Cell. 2012

pdb entry:

4aj5


ASAP core complex
4a8x

Murachelli AG et al. Nat Struct Mol Biol. 2012

pdb entries:

4a8x (ASAP core)

4a6q (Sap18, I222 form)

4a90 (Sap18, C2 form)


Yeast Ski2 RNA helicase
4a4z

Halbach F et al. RNA. 2012

pdb entries:

4a4z (full length)

4a4k (insertion domain)


Survivin bound to phosphorylated histone H3 tail or shugoshin 1 N-terminus
4a0j

Jeyaprakash AA et al. Structure. 2011

pdb entries:

4a0i (with human Shugoshin 1 N-terminus)

4a0j (with phosphorylated histone H3 tail, C2 form)

4a0n (with phosphorylated histone H3 tail, I222 form)


Helicase domain of human Upf1
2xzp

Chakrabarti S et al. Mol Cell 2011

pdb entry:

2xzp


Helicase domain of human Upf1 with RNA in the transition state
2xzo

Chakrabarti S et al. Mol Cell 2011

pdb entry:

2xzo


CH and Helicase domains of yeast Upf1 with RNA in the transition state
2xzl

Chakrabarti S et al. Mol Cell 2011

pdb entry:

2xzl


Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3
3n89

Nakel K et al. RNA. 2010

pdb entry:

3n89


Mtr4 in complex with RNA and ADP
2xgj

Weir JR et al. Proc Natl Acad Sci U S A. 2010

pdb entry:

2xgj


EJC in complex with the C-terminus of Upf3b
2xb2

Buchwald G et al. Proc Natl Acad Sci U S A. 2010

pdb entry:

2xb2


Importin 13 in complex with Mago-Y14
2x1g

Bono F et al. Mol Cell. 2010

pdb entry:

2x1g


Importin 13 in complex with Ran-GTP
2x19

Bono F et al. Mol Cell. 2010

pdb entry:

2x19


Yeast exosome components Rrp41 and Rrp45 in complex with the Rrp44 nuclease
2wp8

Bonneau F, Basquin J et al. Cell. 2009

pdb entry:

2wp8


tRNA export factor: nuclear state
3icq

Cook AG et al. Nature. 2009

pdb entry:

3icq


tRNA export factor: cytosolic state
3ibv

Cook AG et al. Nature. 2009

pdb entry:

3ibv


Dbp5 in complex with RNA and AMPPNP
3fht

von Moeller H et al. Nat Struct Mol Biol. 2009

pdb entry:

3fht


N-terminal domain of Dbp5 in complex with Nup214
3fhc

von Moeller H et al. Nat Struct Mol Biol. 2009

pdb entry:

3fhc


C-terminal region of Drosophila Ge-1
2vxg

Jinek M et al. RNA. 2008

pdb entry:

2vxg


Active Subunit of the Yeast Exosome Core: Rrp44
2vnu

Lorentzen E et al. Mol Cell. 2008

pdb entry:

2vnu


Survivin-Borealin-INCENP Core Complex
2qfa

Jeyaprakash AA et al. Cell. 2007

pdb entry:

2qfa


9-Subunit Archaeal Exosome
2je6

Lorentzen E et al. EMBO Rep. 2007

pdb entries:

2je6

2jea

2jeb


Yeast Exosome Component Rrp40
2ja9

Oddone A et al. EMBO Rep. 2007

pdb entry:

2ja9


Exon Junction Complex
2j0s

Bono F et al. Cell. 2006

pdb entries:

2j0s

2j0q


EIF4AIII-Barentsz Complex
2j0u

Bono F et al. Cell. 2006

pdb entry:

2j0u


Catalytic Domain of Mouse Manic Fringe
2j0a

Jinek M et al. Nat Struct Mol Biol. 2006

pdb entries:

2j0a

2j0b


PIN Domains of SMG5 and SMG6
2hww

Glavan F et al. EMBO J. 2006

pdb entries:

2hww (SMG6)

2hwx

2hwy (SMG5)


RNAse PH Core of the Archaeal Exosome
2br2

Lorentzen E et al. Nat Struct Mol Biol. 2005

Lorentzen E et al. Mol Cell. 2005

pdb entries:

2br2

2c37

2c38

2c39


Exportin Cse1 in its Cargo-free State
1z3h

Cook A et al. Mol Cell. 2005

pdb entry:

1z3h


N-terminal Domain of Human SMG7
1ya0

Fukuhara N et al. Mol Cell. 2005

pdb entry:

1ya0


Superhelical TPR-repeat Domain of O-Linked GlcNAc Transferase
1w3b

Jinek M et al. Nat Struct Mol Biol. 2004

pdb entry:

1w3b


PYM bound to the Mago-Y14 Core of the Exon Junction Complex
1rk8

Bono F et al. EMBO Rep. 2004

pdb entry:

1rk8


Aurora-A bound to TPX2
1ol5

Bayliss R et al. Mol Cell. 2003

Bayliss R et al. Cell Cycle. 2004

pdb entries:

1ol5

1ol6

1ol7


mRNA Export Factor MEX67-MTR2 Complex
1of5

Fribourg S et al. EMBO Rep. 2003

pdb entry:

1of5


NTF2-like Domain of TAP/p15 mRNA Export Factor
1jkg

Fribourg S et al. Mol Cell. 2001

pdb entries:

1jkg

1jn5


Mago-Y14 Complex
1hl6

Fribourg S et al. Nat Struct Biol. 2003

pdb entry:

1hl6


RNA Binding Domain of the mRNA Export Factor TAP
1ft8

Liker E et al. EMBO J. 2000

pdb entries:

1ft8

1fo1


Karyopherin Alpha from Saccharomyces Cerevisiae bound to NLS
1bk6

Conti E et al. Cell. 1998

Conti E et al. Structure. 2000

pdb entries:

1bk5

1bk6

1ee4

1ee5

 
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