MPI für Biochemie  

Molecular Structural Biology
Wolfgang Baumeister

EU-Projects at the MPIB

 

EU FP7 Marie Curie Initial Training Network, Nucleosome4D

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(01.11.2009 - 31.10.2013)

 

Coordinator: Andreas Ladurner, EMBL Heidelberg (LMU, Munich from March 1, 2011 onwards)

Manager: Marzia  Sidri, EMBL Heidelberg (Corey Laverty, LMU Munich from March 1, 2011 onwards)

MPI Group: Juerg Müller

16 Partners (21 Labs) in 11 countries, budget: 4,6 Mio Euro.

The main objective of the Network is to provide young researchers with world-class research & training in chromatin biology. Complementary approaches in structural biology, biophysics, cell biology, live-cell imaging, biochemistry, genetics, genomics and bioinformatics will be used in collaborative projects to determine how nucleosomes are remodeled during transcription, when genes are silenced, as cell divide, as stem cells differentiate, during organismal development and in human disease.


Collaborative Project & CSA "Prime-XS"

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(1.2.2011- 31.1.2015)

 

Coordinator: Albert Heck, Utrecht University

Manager: Reinout Raijmakers, Utrecht University

MPI Group: M.Mann

12 Partners (15 Labs) in 9 countries, budget: 9,8 Mio Euro.

Major objective: to provide state-of-the-art proteomics technologies to the European biological and biomedical research community. The leading proteomic labs forming Prime-XS will provide access to their facilities, develop new technologies, and will disseminate knowledge and expertise through meetings and training events.


Collaborative Project "Euro-MOTOR"

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(1.2.2011-31.1.2016)

 

Coordinator: L. van den Berg, UMC Utrecht

Manager: P. Berk, UMC Utrecht

MPI Group: M.Mann

15 Partners (16 Labs) in 7 countries, budget: 11,8 Mio Euro.

Major objective is a better understanding and treatment of the neurotropic degenerative disease Amyotrophic Lateral Sclerosis. Euro-MOTOR aims to detect key genetic drivers of disease susceptibility/progression and to generate a model of disease which can be validated in patients to pave the way for novel therapeutic interventions for this disabling and fatal disease.


Collaborative Project “ Prospects"

Prospects

(1.4.2008-31.3.2013)

Coordinator: M.Mann, MPI Biochemistry

Manager: AK Werenskiold, MPI Biochemistry

MPI Groups: Mann, Hartl, Baumeister

10 Partners (12 Labs) in 7 countries, budget. 11,7 Mio Euro. Major objectives include the development of much more powerful instrumentation and novel proteomics methods. The goal is to annotate quantitatively the human proteome with respect to protein localization and dynamics.


ESFRI-Project: Instruct

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(Preparatory Phase: 01.04.2008-31.03.2011; Operational Phase: since 01.04.2011)

Coordinator: D. Stuart, University of Oxford

National Coordination:  W. Baumeister, MPI Biochemistry

National Manager: J. Rieder, MPI Biochemistry

 

Preparatory Phase: 12 partners in 5 countries, budget. 4.5 Mio Euro. Major objectives: to set up a framework consisting of distributed centres (during preparatory phase 7 core centres), each of which will maintain a set of core technologies such as protein production, NMR, crystallography and different forms of microscopy, including electron microscopy and combine this with a specific biological focus that will drive the development of technological and methodological expertise, notably for the analysis of functional complexes.

 

Operational Phase: Currently 20 partners in 8 countries, 8 core centres and 7 associate centres. Major objectives: to provide European researchers from academia and industry with access to state-of-the-art structural biology technologies, scientific expertise and training and, by driving innovation at the boundaries between these technologies, stimulate and facilitate research that integrates an understanding of biological structure with cellular function.

 


Integrated Project “Interaction Proteome”

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(1.1.2004-30.6.2009)

Coordinator: F-U. Hartl, MPI Biochemistry
Manager: AK Werenskiold, MPI Biochemistry
11 Partners (14 Labs) in 7 countries, budget. 12 Mio Euro. Major objectives include the establishment of a broadly applicable platform of routine methods for the analysis of protein interaction networks.


Network of Excellence “3D-EM”

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(1.3.2004-31.08.2009)

Coordinator: A. Engel, Biozentrum, Basel
Scientific Manager: AK Werenskiold MPI Biochemistry
16 Partners (18 Labs) in 7 countries, budget. 10 Mio Euro. Major objectives include the establishment of synergies between different technologies in structural research and of an extensive training programme in all fields related to structural biology