Prof. Dr. Danny Nedialkova
Prof. Dr. Danny Nedialkova
Group Leader

MPI of Biochemistry, Am Klopferspitz 18, 82152 Martinsried

Mechanisms of Protein Biogenesis



Mittal N., Guimaraes J., Gross T., Schmidt A., Vina-Vilaseca A., Nedialkova D.D., Aeschimann F., Leidel S.A., Spang A., Zavolan M. 2017. "The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan". Nature Comms 8(1):457

Jungfleisch  J., Nedialkova D.D.*, Dotu I.*, Sloan K.E., Bruening L., Raineri E., Bohnsack M., Leidel S.A., Diez J. 2016. “A novel and conserved translational control mechanism involving RNA structures within coding sequences“. Genome Res., in press. *Equal contribution

Lecanda A., Nilges B.S., Sharma P., Nedialkova D.D., Schwarz J., Vaquerizas J.M., Leidel S.A. 2016. “Dual randomization of oligonucleotides to reduce the bias in ribosome profiling libraries”. Methods 107: 89-97.

Laguesse S.*, Creppe C.*, Nedialkova D.D., Prévot P.-P., Borgs L., Huysseune S., Franco B., Duysens G., Krusy N., Lee G., Thelen N., Thiry M., Close P., Chariot A., Malgrange B., Leidel S.A., Godin J.D., Nguyen L. 2015. “A dynamic unfolded protein response contributes to the control of cortical neurogenesis”. Dev Cell 35 (5): 553-67 *Equal contribution

Nedialkova D.D., Leidel S.A. 2015. “Optimization of codon translation rates via tRNA modifications maintains proteome integrity”. Cell 161 (7): 1606-1618. 

Nedialkova D.D., Gorbalenya A.E., Snijder E.J. 2013. “Arterivirus papain-like proteinase 1α”. Handbook of Proteolytic Enzymes. Oxford: Academic Press, pp. 2199-2204. 

Nedialkova D.D., Gorbalenya A.E., Snijder E.J. 2013. “Arterivirus papain-like proteinase 1β”. Handbook of Proteolytic Enzymes. Oxford: Academic Press, pp. 2205-2210.

Nedialkova D.D., Gorbalenya A.E., Snijder E.J. 2010. “Arterivirus nsp1 modulates the accumulation of minus-strand templates to control the relative abundance of viral mRNAs”. PLoS Pathog. 6(2): e1000772.

Nedialkova D.D., Ulferts R., van den Born E., Lauber C., Gorbalenya A.E., Ziebuhr J., Snijder E.J. 2009. “Biochemical characterization of arterivirus nonstructural protein 11 reveals the nidovirus-wide conservation of a replicative endoribonuclease”. J Virol. 83 (11): 5671–5682.

Tijms M.A*, Nedialkova D.D.*, Zevenhoven-Dobbe J.C.*, Gorbalenya A.E., Snijder E.J. 2007. “Arterivirus subgenomic mRNA synthesis and virion biogenesis depend on the multifunctional nsp1 autoprotease”. J Virol. 81 (19): 10496-505. *Equal contribution

Posthuma C.C., Nedialkova D.D., Zevenhoven-Dobbe J.C., Blokhuis J.H., Gorbalenya A.E., Snijder E.J. 2006. “Site-directed mutagenesis of the nidovirus replicative endoribonuclease NendoU exerts pleiotropic effects on the arterivirus life cycle”. J Virol. 80 (4): 1653-61 [OA]

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