Contact

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Prof. Jürgen Cox, PhD
Group Leader
Phone:+49 89 8578-2088
Email:cox@...

MPI of Biochemistry,
Am Klopferspitz 18, 82152 Martinsried

http://www.biochem.mpg.de/cox

Events

MaxQuant Summer School 2017 in Berlin, Germany

July 3rd - July 7th

For more details click here.

Research

We develop algorithms and tools for analyzing the vast amounts of spectral data that are produced in modern proteomics experiments. The MaxQuant software that we develop is one of the most widely used platforms in computational proteomics. Many labs world-wide benefit from its precise protein and peptide

Mass spectrometry-based proteomics

We develop algorithms and tools for analyzing the vast amounts of spectral data that are produced in modern proteomics experiments. The MaxQuant software that we develop is one of the most widely used platforms in computational proteomics. Many labs world-wide benefit from its precise protein and peptide [more]
One of our main interests lies in the interpretation of quantitative profiles of many proteins or other biomolecules measured simultaneously. Experiments producing such datasets may have many different designs, so a rich arsenal of tools and algorithms is needed to gain

Statistics and bioinformatics for high-throughput biological data

One of our main interests lies in the interpretation of quantitative profiles of many proteins or other biomolecules measured simultaneously. Experiments producing such datasets may have many different designs, so a rich arsenal of tools and algorithms is needed to gain [more]
Modification of a protein with functional groups after the translation of the amino acid chain is a common mechanism of altering its behavior, for instance leading to activation or inactivation. Studying the creation and erasure of these posttranslational modifications (PTMs) in the whole

Posttranslational modifications

Modification of a protein with functional groups after the translation of the amino acid chain is a common mechanism of altering its behavior, for instance leading to activation or inactivation. Studying the creation and erasure of these posttranslational modifications (PTMs) in the whole [more]
The diversity of proteins is greatly increased due to the fact that most of the human multi-exon genes are alternatively spliced. The results of the pre-mRNA splicing can be observed on the mature mRNA or on the protein level. We develop computational methods that

Alternative splicing

The diversity of proteins is greatly increased due to the fact that most of the human multi-exon genes are alternatively spliced. The results of the pre-mRNA splicing can be observed on the mature mRNA or on the protein level. We develop computational methods that [more]
The analysis of proteomics data from patients requires special computational strategies. The problems that need to be addressed include questions like how to extract meaningful protein expression signatures from data with high individual variability, how to integrate the genomic

Clinical proteomics

The analysis of proteomics data from patients requires special computational strategies. The problems that need to be addressed include questions like how to extract meaningful protein expression signatures from data with high individual variability, how to integrate the genomic [more]
 
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